ReviewTraffic (Copenhagen, Denmark)2002
A microbial strategy to multiply in macrophages: the pregnant pause.
Review in Traffic (Copenhagen, Denmark), 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 33 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
33 citing papers in PubMed, 87 citations in OpenAlex.
- Q fever immunology: the quest for a safe and effective vaccine.NPJ vaccines · 2023Review
- Peptidoglycan deacetylation controls type IV secretion and the intracellular survival of the bacterial pathogenProceedings of the National Academy of Sciences of the United States of America · 2023Article
- Persistence of Intracellular Bacterial Pathogens-With a Focus on the Metabolic Perspective.Frontiers in cellular and infection microbiology · 2020Review
- Novel cell-based in vitro screen to identify small-molecule inhibitors against intracellular replication of Cryptococcus neoformans in macrophages.International journal of antimicrobial agents · 2016Article
- Contrasting Lifestyles Within the Host Cell.Microbiology spectrum · 2016Review
- Article
- Differential influence of nutrient-starved Mycobacterium tuberculosis on adaptive immunity results in progressive tuberculosis disease and pathology.Infection and immunity · 2015Article
- Coxiella burnetii and Leishmania mexicana residing within similar parasitophorous vacuoles elicit disparate host responses.Frontiers in microbiology · 2015Article
- Essential role for the response regulator PmrA in Coxiella burnetii type 4B secretion and colonization of mammalian host cells.Journal of bacteriology · 2014Article
- How positive-strand RNA viruses benefit from autophagosome maturation.Journal of virology · 2013Review
- Intracellular vesicle acidification promotes maturation of infectious poliovirus particles.PLoS pathogens · 2012Article
- Sleeping with the enemy: how intracellular pathogens cope with a macrophage lifestyle.PLoS pathogens · 2012Article
- Multiple levels of gene regulation mediate differentiation of the intracellular pathogen Leishmania.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2011Article
- RpkA, a highly conserved GPCR with a lipid kinase domain, has a role in phagocytosis and anti-bacterial defense.PloS one · 2011Article
- Evidence that intracellular stages of Leishmania major utilize amino sugars as a major carbon source.PLoS pathogens · 2010Article
- Control of flagellar gene regulation in Legionella pneumophila and its relation to growth phase.Journal of bacteriology · 2010Article
- Antimicrobial mechanisms of phagocytes and bacterial evasion strategies.Nature reviews. Microbiology · 2009Review
- The Legionella pneumophila replication vacuole: making a cosy niche inside host cells.Nature reviews. Microbiology · 2009Review
- A network of Rab GTPases controls phagosome maturation and is modulated by Salmonella enterica serovar Typhimurium.The Journal of cell biology · 2007Article
- Helicobacter pylori VacA toxin promotes bacterial intracellular survival in gastric epithelial cells.Infection and immunity · 2006Article
Corrections and comments
- Erratum issuedFernandez-Moreia Esteban [corrected to Fernandez-Moreira Esteban]
Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
Humans live in harmony with much of the microbial world, thanks to a sophisticated immune system. As the first line of defense, macrophages engulf, digest, and display foreign material, then recruit specialists to eliminate potential threats. Yet infiltrators exist: certain fungi, viruses, parasites, and bacteria thrive within sentinel macrophages. By scrutinizing the life styles of these shrewd microbes, we can deduce how macrophages routinely mount an effective immune response. The bimorphic life cycles of three pathogens have dramatic consequences for phagosome traffic. In the transmissible state, Leishmania spp., Coxiella burnetii, and Legionella pneumophila block phagosome maturation; after a pregnant pause, replicative forms emerge and thrive in lysosomes.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.