ArticleThe Plant cell2002
The putative plasma membrane Na(+)/H(+) antiporter SOS1 controls long-distance Na(+) transport in plants.
Article in The Plant cell, 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 451 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
451 citing papers in PubMed, 1,295 citations in OpenAlex.
- BnaGRP3 mediates salt tolerance via NaJournal of advanced research · 2026Article
- Cyclic nucleotide-gated channels 14, 15, and 16 coordinate multiple signaling pathways to promote salt tolerance in rice.The Plant journal : for cell and molecular biology · 2026Article
- Root Structural and Metabolic Plasticity Confers Tolerance to Salinity in Wild Barley Species Grown Under Waterlogging.Plant, cell & environment · 2026Article
- Insights into Salinity Stress-Induced Morpho-Physiological and Molecular Responses and Nanoparticle- and Nanobiochar-Mediated Tolerance Mechanisms During Seed Germination.Nanomaterials (Basel, Switzerland) · 2026Review
- Genome-Wide Identification of the WheatPlants (Basel, Switzerland) · 2026Article
- The architecture of salt tolerance: A multi-scale view of sodium transport in plants.Plant communications · 2026Review
- Dissecting the genetic switches controlling salt tolerance in bermudagrass (Cynodon dactylon).The Plant cell · 2026Article
- Tomato plants control leaf sodium levels to limit damage by Spodoptera littoralis larvae.The New phytologist · 2026Article
- Genome-wide identification and salt stress-induced expression analysis of the NHX gene family in peanut (Arachis hypogaea L.).BMC plant biology · 2026Article
- Salinity tolerance in wheat: rethinking the targets.Journal of experimental botany · 2026Review
- Fulvic Acid Suppresses Excessive Cytokinin Biosynthesis to Reduce ROS Content and thus Decrease NaRice (New York, N.Y.) · 2026Article
- Nano-priming modulates antioxidant enzymes and NHX/SOS-mediated ion homeostasis to improve salinity tolerance in barley genotypes.Plant cell reports · 2026Article
- Evolutionary Dynamics of theGenes · 2026Article
- Article
- SALT OVERLY SENSITIVE 1 NaPlant, cell & environment · 2026Article
- Arbuscular mycorrhizal fungi as integrative modulators of plant tolerance to drought, salinity, and heavy metal stress: mechanistic insights and future directions.Journal, genetic engineering & biotechnology · 2026Review
- Plant Adaptation to Salinity: Physiological Pathways and Prospects for Crop Improvement-A Review.Genes · 2026Review
- Phytomelatonin in Ornamental Horticulture: A Comprehensive Review of Growth Promotion, Stress Tolerance, and Post-Harvest Quality.International journal of molecular sciences · 2026Review
- Mechanistic insights and breeding prospects of secondary metabolites in wheat salt stress tolerance.Planta · 2026Review
- Integrating multiomic resources and gene expression studies to identify candidates for engineering climate-resilientFrontiers in plant science · 2026Review
391 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
Abstract
The salt tolerance locus SOS1 from Arabidopsis has been shown to encode a putative plasma membrane Na(+)/H(+) antiporter. In this study, we examined the tissue-specific pattern of gene expression as well as the Na(+) transport activity and subcellular localization of SOS1. When expressed in a yeast mutant deficient in endogenous Na(+) transporters, SOS1 was able to reduce Na(+) accumulation and improve salt tolerance of the mutant cells. Confocal imaging of a SOS1-green fluorescent protein fusion protein in transgenic Arabidopsis plants indicated that SOS1 is localized in the plasma membrane. Analysis of SOS1 promoter-beta-glucuronidase transgenic Arabidopsis plants revealed preferential expression of SOS1 in epidermal cells at the root tip and in parenchyma cells at the xylem/symplast boundary of roots, stems, and leaves. Under mild salt stress (25 mM NaCl), sos1 mutant shoot accumulated less Na(+) than did the wild-type shoot. However, under severe salt stress (100 mM NaCl), sos1 mutant plants accumulated more Na(+) than did the wild type. There also was greater Na(+) content in the xylem sap of sos1 mutant plants exposed to 100 mM NaCl. These results suggest that SOS1 is critical for controlling long-distance Na(+) transport from root to shoot. We present a model in which SOS1 functions in retrieving Na(+) from the xylem stream under severe salt stress, whereas under mild salt stress it may function in loading Na(+) into the xylem.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.