ArticleThe Plant cell2002
AXR1-ECR1-dependent conjugation of RUB1 to the Arabidopsis Cullin AtCUL1 is required for auxin response.
Article in The Plant cell, 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 106 papers.
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Who cites it
106 citing papers in PubMed.
- Auxin-Dependent Activation of RHD6-RSL4 Cascade Promotes Root Hair Growth Under Boron Deficiency in Arabidopsis Primary Root Apices.Plant, cell & environment · 2026Article
- Article
- RACK1A positively regulates opening of the apical hook inProceedings of the National Academy of Sciences of the United States of America · 2025Article
- Moisture-responsive root-branching pathways identified in diverse maize breeding germplasm.Science (New York, N.Y.) · 2025Article
- Protein degradation in auxin response.The Plant cell · 2024Review
- Unlocking the Multifaceted Mechanisms of Bud Outgrowth: Advances in Understanding Shoot Branching.Plants (Basel, Switzerland) · 2023Review
- Genome-wide identification of RUB activating enzyme and conjugating enzyme gene families and their expression analysis under abiotic stresses in Capsicum annuum.Protoplasma · 2023Article
- Analyses of Cullin1 homologs reveal functional redundancy in S-RNase-based self-incompatibility and evolutionary relationships in eudicots.The Plant cell · 2023Article
- Comparative transcriptome analysis of molecular mechanisms underlying adventitious root developments in Huangshan Bitter tea (Frontiers in plant science · 2023Article
- Insights into the plateau adaptation of Salvia castanea by comparative genomic and WGCNA analyses.Journal of advanced research · 2022Article
- Article
- Structural Aspects of Auxin Signaling.Cold Spring Harbor perspectives in biology · 2022Review
- The chemical compound 'Heatin' stimulates hypocotyl elongation and interferes with the Arabidopsis NIT1-subfamily of nitrilases.The Plant journal : for cell and molecular biology · 2021Article
- Molecular mechanism of lateral bud differentiation of Pinus massoniana based on high-throughput sequencing.Scientific reports · 2021Article
- Duplication and divergence: New insights into AXR1 and AXL functions in DNA repair and meiosis.Scientific reports · 2020Article
- The Antioxidant Enzyme Methionine Sulfoxide Reductase A (MsrA) Interacts with Jab1/CSN5 and Regulates Its Function.Antioxidants (Basel, Switzerland) · 2020Article
- Review
- Article
- Transcriptomics of cytokinin and auxin metabolism and signaling genes during seed maturation in dormant and non-dormant wheat genotypes.Scientific reports · 2019Article
- Identification of Auxin Activity Like 1, a chemical with weak functions in auxin signaling pathway.Plant molecular biology · 2018Article
46 more citing papers are in PubMed but not listed here.
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6 authors.
Funding
Abstract
Mutations in the AXR1 gene result in a reduction in auxin response and diverse defects in auxin-regulated growth and development. In a previous study, we showed that AXR1 forms a heterodimer with the ECR1 protein. This enzyme activates the ubiquitin-related protein RUB1 in vitro. Furthermore, we showed that the Skp1-Cul1/Cdc53-F-box (SCF) subunit AtCUL1 is modified by RUB1 in vivo. In this report, we demonstrate that the formation of RUB-AtCUL1 is dependent on AXR1 and ECR1 in vivo. The expression of AXR1 and ECR1 is restricted to zones of active cell division and cell elongation, consistent with their role in growth regulation. These results provide strong support for a model in which RUB conjugation of AtCUL1 affects the function of SCF E3s that are required for auxin response.
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