Evidence map›Paper›PMID 11884273›Full record

ReviewCurrent hypertension reports2002

Angiotensin II-mediated signal transduction pathways.

Yuji Saito, Bradford C Berk

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current hypertension reports, 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
5.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 67 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Cardiomyocyte-SpecificJournal of the American Heart Association · 2019
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Experimental validation of miRNA targets.Methods (San Diego, Calif.) · 2008
    Review
  13. Article
  14. Article
  15. The renin-angiotensin system and atherosclerosis.Current hypertension reports · 2006
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Yuji SaitoCenter for Cardiovascular Research, University of Rochester, 601 Elmwood Avenue, Box 679, Rochester, NY 14642, USA.
Bradford C Berk
University of Rochester · US

Funding

Oxidative Stress and Vascular Smoth Muscle Cell GrowthR01HL049192 · NHLBI · UNIVERSITY OF WASHINGTON · PI BERK, BRADFORD C · 1995 to 2019
$6.1M
NHLBI NIH HHS HL-49192NHLBI NIH HHS HL 59975
6 · The paper itself

Abstract

The renin-angiotensin system is one of the major cardiovascular systems that controls blood volume, peripheral vascular tone, and blood pressure. Recent studies indicate important roles for angiotensin II in inflammation, atherosclerosis, and congestive heart failure as well. It is gradually becoming clear that angiotensin II exerts effects on the cardiovascular system through several unique mechanisms, including the availability of two different angiotensin II receptors, recruitment of protein tyrosine kinase activity, and receptor tyrosine kinase transactivation. This review discusses the diverse mechanisms of angiotensin II-mediated signal transduction pathways and the various effects of angiotensin II on the cardiovascular system.

Indexed as

Angiotensin IICardiovascular SystemHumansReceptor Protein-Tyrosine KinasesReceptors, AngiotensinRenin-Angiotensin SystemSignal TransductionThymidine PhosphorylaseTranscriptional ActivationAngiotensin IIReceptor Protein-Tyrosine KinasesReceptors, AngiotensinThymidine Phosphorylase

Identifiers

PMID11884273
OpenAlexW2011239555

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.