ArticleEnvironmental health perspectives2002
Childhood cancer and agricultural pesticide use: an ecologic study in California.
Article in Environmental health perspectives, 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00015587 (Chemical Exposures and Leukemia Risks and Childhood Leukemia and Environmental Exposure), which is not on this map. Cited by 47 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Chemical Exposures and Leukemia Risks and Childhood Leukemia and Environmental Exposure
Who cites it
47 citing papers in PubMed, 3 syntheses or guidelines pooled it, 128 citations in OpenAlex.
- Passive environmental residential exposure to agricultural pesticides and hematological malignancies in the general population: a systematic review.Environmental science and pollution research international · 2021Pooled it
- Prostate cancer and toxicity from critical use exemptions of methyl bromide: environmental protection helps protect against human health risks.Environmental health : a global access science source · 2012Pooled it
- Cancer health effects of pesticides: systematic review.Canadian family physician Medecin de famille canadien · 2007Pooled it
- Relative risk of childhood and adolescence cancer in Iran: spatiotemporal analysis from 1999 to 2016.BMC research notes · 2024Article
- Association between Residential Proximity to Viticultural Areas and Childhood Acute Leukemia Risk in Mainland France: GEOCAP Case-Control Study, 2006-2013.Environmental health perspectives · 2023Article
- Amyotrophic Lateral Sclerosis and Air Pollutants in the Province of Ferrara, Northern Italy: An Ecological Study.International journal of environmental research and public health · 2023Article
- Integrating Environmental Data with Medical Data in a Records-Linkage System to Explore Groundwater Nitrogen Levels and Child Health Outcomes.International journal of environmental research and public health · 2023Article
- Residential proximity to croplands at birth and childhood leukaemia.Environmental health : a global access science source · 2022Article
- Residential proximity to pesticide application as a risk factor for childhood central nervous system tumors.Environmental research · 2021Article
- Development of A Liquid Chromatography-Mass Spectrometry Technique for Evaluation of Multi-class Pesticides in Rice Samples.Iranian journal of pharmaceutical research : IJPR · 2021Article
- Risk of genotoxic damage in schoolchildren exposed to organochloride pesticides.Scientific reports · 2020Article
- Residential proximity to agriculture and risk of childhood leukemia and central nervous system tumors in the Danish national birth cohort.Environment international · 2020Article
- Prenatal pesticide exposure and childhood leukemia - A California statewide case-control study.International journal of hygiene and environmental health · 2020Article
- Passive exposure to agricultural pesticides and risk of childhood leukemia in an Italian community.International journal of hygiene and environmental health · 2016Article
- Agricultural crop density and risk of childhood cancer in the midwestern United States: an ecologic study.Environmental health : a global access science source · 2015Article
- Genetic and nongenetic risk factors for childhood cancer.Pediatric clinics of North America · 2015Review
- Pesticide exposure in children.Pediatrics · 2012Article
- Residential proximity to environmental hazards and adverse health outcomes.American journal of public health · 2011Review
- Effect of endocrine disruptor pesticides: a review.International journal of environmental research and public health · 2011Review
- Residential proximity to agricultural pesticide applications and childhood acute lymphoblastic leukemia.Environmental research · 2009Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 1 country.
Funding
Abstract
We analyzed population-based childhood cancer incidence rates throughout California in relation to agricultural pesticide use. During 1988-1994, a total of 7,143 cases of invasive cancer were diagnosed among children under 15 years of age in California. Building on the availability of high-quality population-based cancer incidence information from the California Cancer Registry, population data from the U.S. Census, and uniquely comprehensive agricultural pesticide use information from California's Department of Pesticide Regulation, we used a geographic information system to assign summary population, exposure, and outcome attributes at the block group level. We used Poisson regression to estimate rate ratios (RRs) by pesticide use density adjusted for race/ethnicity, age, and sex for all types of childhood cancer combined and separately for the leukemias and central nervous system cancers. We generally found no association between pesticide use density and childhood cancer incidence rates. The RR for all cancers was 0.95 [95% confidence interval (CI), 0.80-1.13] for block groups in the 90th percentile and above for use of pesticides classified as probable carcinogens, compared to the block groups with use of < 1 lb/mi(2). The RRs were similar for leukemia and central nervous system cancers. Childhood leukemia rates were significantly elevated (RR = 1.48; 95% CI, 1.03-2.13) in block groups with the highest use of propargite, although we saw no dose-response trend with increasing exposure categories. Results were unchanged by further adjustment for socioeconomic status and urbanization.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.