Evidence map›Paper›PMID 11880416›Full record

ArticleJournal of clinical microbiology2002

Susceptibility testing of fluconazole by the NCCLS broth macrodilution method, E-test, and disk diffusion for application in the routine laboratory.

Inge Vandenbossche, Mario Vaneechoutte, Marleen Vandevenne, Thierry De Baere, Gerda Verschraegen

Open access · greenAbstract read
In one paragraph

Article in Journal of clinical microbiology, 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 67 citations in OpenAlex.

  1. Article
  2. Article
  3. Can We Improve Antifungal Susceptibility Testing?Frontiers in cellular and infection microbiology · 2021
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  5. Antifungal susceptibility testing of vulvovaginalInfection and drug resistance · 2018
    Article
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  8. Article
  9. Profile of yeasts isolated from urinary tracts of catheterized patients.Journal of clinical and diagnostic research : JCDR · 2014
    Article
  10. Fungal scleral keratitis caused by Phomopsis phoenicicola.Journal of clinical microbiology · 2011
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Inge VandenbosscheDepartment of Clinical Chemistry, Microbiology and Immunology, Ghent University Hospital, Ghent, Belgium. Ingevdb2002@yahoo.com
Mario Vaneechoutte
Marleen Vandevenne
Thierry De Baere
Gerda Verschraegen
Ghent University Hospital · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Antifungal susceptibility testing may be an important aid in the treatment of patients with life-threatening yeast infections. In order to establish the suitability of different susceptibility test methods for fluconazole with yeasts, the Rosco tablet and the E-test were compared with the gold standard NCCLS broth macrodilution method for 106 yeast strains. These included 102 clinical isolates of Candida spp., including Candida glabrata (n = 30), Candida albicans (n = 20), Candida tropicalis (n = 13), Candida parapsilosis (n = 10), Candida krusei (n = 8), plus Cryptococcus neoformans (n = 3), Saccharomyces cerevisiae (n = 2), and 16 strains belonging to other Candida spp. Four American Type Culture Collection strains of Candida were included as quality controls. The NCCLS method was found to be too complex and labor-intensive for routine testing. The E-test is an accurate alternative, but experience in determining MICs and careful attention to procedural details are critically important. The Rosco tablet showed the best agreement with the NCCLS reference method, especially when newly established breakpoints of R < or = 10 mm and S > or = 21 mm were used.

Indexed as

Antifungal AgentsDiffusionFluconazoleFungiHumansMicrobial Sensitivity TestsAntifungal AgentsFluconazole

Identifiers

PMID11880416
PMCPMC120224
OpenAlexW2111204030

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.