ReviewBreast cancer research : BCR2002
E-cadherin and loss of heterozygosity at chromosome 16 in breast carcinogenesis: different genetic pathways in ductal and lobular breast cancer?
Review in Breast cancer research : BCR, 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
33 citing papers in PubMed, 124 citations in OpenAlex.
- Cytogenetic alterations and coagulopathy in breast cancer patients: molecular mechanisms and clinical implications.Annals of medicine and surgery (2012) · 2026Review
- Spatial molecular profiling of mixed invasive ductal and lobular breast cancers reveals heterogeneity in intrinsic molecular subtypes, oncogenic signatures, and mutations.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Association betweenRadiology and oncology · 2023Article
- Article
- Primary Signet Ring Cell/Histiocytoid Carcinoma of the Eyelid: Clinicopathologic Analysis with Evaluation of the E-Cadherin/Case reports in pathology · 2021Article
- E-cadherin immunohistochemical expression in invasive lobular carcinoma of the breast: correlation with morphology and CDH1 somatic alterations.Human pathology · 2020Article
- The molecular mechanisms underlying reduced E-cadherin expression in invasive ductal carcinoma of the breast: high throughput analysis of large cohorts.Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc · 2019Article
- Downregulation of regulator of G protein signaling 2 expression in breast invasive carcinoma of no special type: Clinicopathological associations and prognostic relevance.Oncology letters · 2018Article
- Gastric and colon metastasis from breast cancer: case report, review of the literature, and possible underlying mechanisms.Breast cancer (Dove Medical Press) · 2017Article
- Is there an association between invasive lobular carcinoma of the breast and a family history of gastric cancer?Familial cancer · 2016Article
- Invasive lobular carcinoma of the breast: morphology, biomarkers and 'omics.Breast cancer research : BCR · 2015Review
- Elevated expression of E-cadherin in primary breast cancer and its corresponding metastatic lymph node.International journal of clinical and experimental medicine · 2015Article
- Evaluation of p53, HoxD10, and E-Cadherin Status in Breast Cancer and Correlation with Histological Grade and Other Prognostic Factors.Journal of oncology · 2014Article
- Altered expression of β-catenin, E-cadherin, and E-cadherin promoter methylation in epithelial ovarian carcinoma.Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine · 2013Article
- Gastric and endobronchial metastases in a case of lobular breast cancer.Case reports in oncology · 2013Article
- Oncogene amplification in male breast cancer: analysis by multiplex ligation-dependent probe amplification.Breast cancer research and treatment · 2012Article
- Cadherin-catenin complex dissociation in lobular neoplasia of the breast.Breast cancer research and treatment · 2012Article
- Molecular differences between ductal carcinoma in situ and adjacent invasive breast carcinoma: a multiplex ligation-dependent probe amplification study.Cellular oncology (Dordrecht, Netherlands) · 2011Article
- Clinicopathlogic and immunohistochemical characteristics of triple negative invasive lobular carcinoma.Yonsei medical journal · 2011Article
- HER2/ErbB2-induced breast cancer cell migration and invasion require p120 catenin activation of Rac1 and Cdc42.The Journal of biological chemistry · 2010Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Loss of heterozygosity at the long arm of chromosome 16 is one of the most frequent genetic events in breast cancer. In the search for tumour suppressor genes that are the target of loss of heterozygosity at 16q, the E-cadherin gene CDH1 was unveiled by the identification of truncating mutations in the retained copy. However, only lobular tumours showed E-cadherin mutations. Whereas investigations are still devoted to finding the target genes in the more frequent ductal breast cancers, other studies suspect the E-cadherin gene to also be the target in this tumour type. The present article discusses the plausibility of those two lines of thought.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.