ArticleBritish journal of cancer2002
A case-control study of childhood leukaemia and paternal occupational contact level in rural Sweden.
Article in British journal of cancer, 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
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Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Preconception care: caffeine, smoking, alcohol, drugs and other environmental chemical/radiation exposure.Reproductive health · 2014Pooled it
- Article
- High parental occupational social contact and risk of childhood hematopoietic, brain and bone cancers.Cancer epidemiology · 2019Article
- A case-control study of occupational contact levels in the childhood leukaemia cluster at Seascale, Cumbria, UK.BMJ open · 2015Article
- Case-control study of paternal occupation and social class with risk of childhood central nervous system tumours in Great Britain, 1962-2006.British journal of cancer · 2013Article
- Case-control study of paternal occupation and childhood leukaemia in Great Britain, 1962-2006.British journal of cancer · 2012Article
- Cancer clusters in the USA: what do the last twenty years of state and federal investigations tell us?Critical reviews in toxicology · 2012Review
- Childhood leukaemia, nuclear sites, and population mixing.British journal of cancer · 2011Review
- Seroprevalence of human herpes simplex, hepatitis B and epstein-barr viruses in children with acute lymphoblastic leukemia in southern iran.Pathology oncology research : POR · 2010Article
- Childhood leukaemia and population movements in France, 1990-2003.British journal of cancer · 2008Article
- Parental social contact in the work place and the risk of childhood acute lymphoblastic leukaemia.British journal of cancer · 2007Article
- Human herpes virus 6 or Epstein-Barr virus were not detected in Guthrie cards from children who later developed leukaemia.British journal of cancer · 2004Article
- Childhood leukaemia incidence and the population mixing hypothesis in US SEER data.British journal of cancer · 2004Article
- Infection and pediatric acute lymphoblastic leukemia.Blood cells, molecules & diseasesReview
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In a national case-control study in Sweden, we investigated whether in rural areas (where susceptible individuals are more prevalent than in urban areas) leukaemia risk was higher among the young children of fathers with many work contacts, as the infective hypothesis has predicted. A total of 1935 cases diagnosed in 1958-1998 together with 7736 age-matched (within 1 year) population controls (of whom 970 and 3880 respectively were aged 0-4) were linked to paternal occupational details as recorded in the census closest to the year of birth. Applying the two classifications of occupational contact level used in a study of rural Scotland, the odds ratios for children aged 0-4 years in the highest contact category (which includes teachers) in the most rural Swedish counties were 3.47 (95% CI 1.54, 7.85) and 1.59 (1.07, 2.38) respectively, relative to the medium and low (reference) category; no such excess was found in urban or intermediate counties. There was also a significant positive trend at ages 0-4 in the rural counties across the three levels of increasing occupational contact (P for trend 0.02 and 0.03, respectively), but again not in the urban or intermediate counties. No such effect or trend was found at ages 5-14 in any of the three county groupings. The findings confirm those of a recent study in rural Scotland, and also suggest that unusual population mixing (as occurred in Scotland as a result of the North Sea oil industry) is not a necessary requirement for the effect, since comparable mixing has not been a feature of rural Sweden.
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