Evidence map›Paper›PMID 11875126›Full record

ReviewMicrobiology and molecular biology reviews : MMBR2002

Cytoskeleton of apicomplexan parasites.

Naomi S Morrissette, L David Sibley

Open access · greenAbstract readReview
In one paragraph

Review in Microbiology and molecular biology reviews : MMBR, 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 217 papers.

0numbers the graph read from it
0cells of the map it votes in
217citing papers in PubMed
13.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

217 citing papers in PubMed, 485 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Two anchoring proteins control daughter apical complex assembly inbioRxiv : the preprint server for biology · 2026
    Article
  9. Microtubule inner proteins in apicomplexan parasites.Biochemical Society transactions · 2026
    Review
  10. Article
  11. The essential function of the apical polar ring during the blood stage ofbioRxiv : the preprint server for biology · 2026
    Article
  12. Article
  13. Atomic models of the Toxoplasma cell invasion machinery.Nature structural & molecular biology · 2026
    Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. Article
  19. Article
  20. Molecular features of Myosin F adapted for driving actin flows inbioRxiv : the preprint server for biology · 2025
    Article

157 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Naomi S MorrissetteDepartment of Molecular Microbiology, Washington University School of Medicine, St. Louis, Missouri 63110, USA. naomi@borcim.wustl.edu
L David Sibley
Washington University in St. Louis · US

Funding

PROTEIN SECRETION &INTRACELLULAR SURVIVAL BY TOXOPLASMAR01AI034036 · NIAID · WASHINGTON UNIVERSITY · PI SIBLEY, L. DAVID · 1993 to 2019
$7.9M
Toxoplasma and Plasmodium resistance to dinitroanilinesF32GM020484 · NIGMS · WASHINGTON UNIVERSITY · PI MORRISSETTE, NAOMI S · 2001 to 2002
$75k
NIAID NIH HHS R01 AI034036NIAID NIH HHS T32 AI-0717221NIGMS NIH HHS F32 GM020484NIGMS NIH HHS F32 GM20484-01A1
6 · The paper itself

Abstract

The Apicomplexa are a phylum of diverse obligate intracellular parasites including Plasmodium spp., the cause of malaria; Toxoplasma gondii and Cryptosporidium parvum, opportunistic pathogens of immunocompromised individuals; and Eimeria spp. and Theileria spp., parasites of considerable agricultural importance. These protozoan parasites share distinctive morphological features, cytoskeletal organization, and modes of replication, motility, and invasion. This review summarizes our current understanding of the cytoskeletal elements, the properties of cytoskeletal proteins, and the role of the cytoskeleton in polarity, motility, invasion, and replication. We discuss the unusual properties of actin and myosin in the Apicomplexa, the highly stereotyped microtubule populations in apicomplexans, and a network of recently discovered novel intermediate filament-like elements in these parasites.

Indexed as

AnimalsApicomplexaCytoskeletonProtozoan Infections

Identifiers

PMID11875126
PMCPMC120781
OpenAlexW2113982265

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.