ArticleAnnals of the rheumatic diseases2002
Which patients stop working because of rheumatoid arthritis? Results of five years' follow up in 732 patients from the Early RA Study (ERAS).
Article in Annals of the rheumatic diseases, 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 61 papers, 3 of them syntheses that pooled it.
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Who cites it
61 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Health Assessment Questionnaire disability progression in early rheumatoid arthritis: systematic review and analysis of two inception cohorts.Seminars in arthritis and rheumatism · 2014Pooled it
- Long term safety of etanercept in elderly subjects with rheumatic diseases.Annals of the rheumatic diseases · 2006Pooled it
- Predictive factors of work disability in rheumatoid arthritis: a systematic literature review.Annals of the rheumatic diseases · 2004Pooled it
- Estimated medical expenditure and risk of job loss among rheumatoid arthritis patients undergoing tofacitinib treatment: post hoc analyses of two randomized clinical trials.Rheumatology (Oxford, England) · 2017Trial
- Trial
- Efficacy & safety evaluation of Ayurvedic treatment (Ashwagandha powder & Sidh Makardhwaj) in rheumatoid arthritis patients: a pilot prospective study.The Indian journal of medical research · 2015Trial
- Effect evaluation of a self-management program for dutch workers with a chronic somatic disease: a randomized controlled trial.Journal of occupational rehabilitation · 2013Trial
- Sick leave as a predictor of job loss in patients with chronic arthritis.International archives of occupational and environmental health · 2006Trial
- [Assessment of the earning capacity of patients with rheumatoid arthritis].Zeitschrift fur Rheumatologie · 2026Article
- Endorsement of reporting guidelines and clinical trial registration across Scopus-indexed rheumatology journals: a cross-sectional analysis.Rheumatology international · 2024Article
- Predictors of DAPSA28 remission in patients with psoriatic arthritis initiating a first TNF inhibitor: results from 13 European registries.Rheumatology (Oxford, England) · 2024Article
- A prospective cohort study of presenteeism and increased risk of unemployment among Japanese workers during the COVID-19 pandemic.Journal of occupational health · 2024Article
- Employment of patients with rheumatoid arthritis - a systematic review and meta-analysis.BMC rheumatology · 2023Article
- Causality of occupational exposure on rheumatoid arthritis and ankylosing spondylitis: a two-sample mendelian randomization study.Frontiers in immunology · 2023Article
- Big data analyses and individual health profiling in the arena of rheumatic and musculoskeletal diseases (RMDs).Therapeutic advances in musculoskeletal disease · 2022Review
- Functionality assessment in patients with rheumatic diseases undergoing treatment in the Public Health System.Einstein (Sao Paulo, Brazil) · 2022Article
- Functional coding haplotypes and machine-learning feature elimination identifies predictors of Methotrexate Response in Rheumatoid Arthritis patients.EBioMedicine · 2022Article
- Predictors of presenteeism, absenteeism and job loss in patients commencing methotrexate or biologic therapy for rheumatoid arthritis.Rheumatology (Oxford, England) · 2020Article
- "I Would be More of a Liability than an Asset": Navigating the Workplace as a Younger Person with Arthritis.Journal of occupational rehabilitation · 2020Article
- The impact of disease severity and duration on cost, early retirement and ability to work in rheumatoid arthritis in Europe: an economic modelling study.Rheumatology advances in practice · 2020Article
1 more citing papers are in PubMed but not listed here.
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12 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo assess the occurrence and prognostic factors for the ability to maintain paid work in patients with rheumatoid arthritis (RA).
settingInception cohort of patients with RA recruited from rheumatology departments in nine NHS Hospital Trusts in England. PATIENTS: All consecutive patients with RA of less than two years' duration, before any second line (disease modifying) drug treatment, and followed up for five years.
methodsClinical, laboratory, and radiological assessments, and all treatments were recorded prospectively using a standardised format at presentation and yearly. OUTCOME MEASURES: Changes in, and loss of paid work by five years' follow up.
results732 patients completed the five year follow up. 353/721 (49%) were gainfully employed at the onset of RA, 211 (60%) were still working at five years, 104 (29%) stopped because of the disease, and 31 (9%) retired for reasons other than RA. Work disability at five years was more likely in manual workers (odds ratio (OR) 2.3, 95% confidence interval (CI) 1.4 to 3.8) and worse baseline Health Assessment Questionnaire (HAQ>1.5, OR 2.26, 95% CI 1.38 to 3.7). In combination with other baseline variables (erythrocyte sedimentation rate, sex, age of onset, and radiological erosions), employment outcome was predicted in 78% using multivariate analysis.
conclusionsNearly half of the patients with RA were in paid employment at onset, work disability was an adverse outcome for a third of these patients by five years, and manual work and high baseline HAQ were important predictors for this. These details are likely to be useful to clinicians, health professionals, and patients in order to plan medical, orthopaedic, and remedial treatments in early RA. Future disease modifying treatments could be compared with this cohort of patients who were treated with conventional second line drugs.
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