ArticleJournal of bacteriology2002
Partitioning of chromosomal DNA during establishment of cellular asymmetry in Bacillus subtilis.
Article in Journal of bacteriology, 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
13 citing papers in PubMed.
- Cohesion of Sister Chromosome Termini during the Early Stages of Sporulation in Bacillus subtilis.Journal of bacteriology · 2020Article
- Article
- Hard-Wired Control of Bacterial Processes by Chromosomal Gene Location.Trends in microbiology · 2016Review
- Missense Mutations Allow a Sequence-Blind Mutant of SpoIIIE to Successfully Translocate Chromosomes during Sporulation.PloS one · 2016Article
- Sequence-directed DNA export guides chromosome translocation during sporulation in Bacillus subtilis.Nature structural & molecular biology · 2008Article
- Cell-specific SpoIIIE assembly and DNA translocation polarity are dictated by chromosome orientation.Molecular microbiology · 2007Article
- Transport capabilities of eleven gram-positive bacteria: comparative genomic analyses.Biochimica et biophysica acta · 2007Review
- DNA segregation by the bacterial actin AlfA during Bacillus subtilis growth and development.The EMBO journal · 2006Article
- Diversity and redundancy in bacterial chromosome segregation mechanisms.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2005Review
- Septal localization of forespore membrane proteins during engulfment in Bacillus subtilis.The EMBO journal · 2004Article
- Chromosome segregation in Eubacteria.Current opinion in microbiology · 2003Review
- The master regulator for entry into sporulation in Bacillus subtilis becomes a cell-specific transcription factor after asymmetric division.Genes & development · 2003Article
- MinCD-dependent regulation of the polarity of SpoIIIE assembly and DNA transfer.The EMBO journal · 2002Article
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
The switch from symmetric to asymmetric cell division is a key feature of development in many organisms, including Bacillus subtilis sporulation. Here we demonstrate that, prior to the onset of asymmetric cell division, the B. subtilis chromosome is partitioned into two unequally sized domains, with the origin-proximal one-third of the future forespore chromosome condensed near one pole of the cell. Asymmetric chromosome partitioning is independent of polar division, as it occurs in cells depleted of FtsZ but depends on two transcription factors that govern the initiation of sporulation, sigma(H) and Spo0A-P. It is also independent of chromosome partitioning proteins Spo0J and Soj, suggesting the existence of a novel mechanism controlling chromosome structure. Thus, our results demonstrate that, during sporulation, two separable events prepare B. subtilis for asymmetric cell division: the relocation of cell division sites to the cell poles and the asymmetric partitioning of the future forespore chromosome.
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