ArticleGenetics2002
Joint linkage and linkage disequilibrium mapping of quantitative trait loci in natural populations.
Article in Genetics, 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
35 citing papers in PubMed, 86 citations in OpenAlex.
- MAGIC populations: a next-generation framework for dissecting complex quantitative traits and accelerating molecular breeding in crops.Frontiers in plant science · 2026Review
- Non-invasive prenatal testing of beta-hemoglobinopathies using next generation sequencing, in-silico sequence size selection, and haplotyping.Croatian medical journal · 2024Article
- The Genetic Architecture of Juvenile Growth Traits in the ConiferFrontiers in plant science · 2022Article
- Association between molecular markers and behavioral phenotypes in the immatures of a butterfly.Genetics and molecular biology · 2018Article
- A Bivariate Hypothesis Testing Approach for Mapping the Trait-Influential Gene.Scientific reports · 2017Article
- Multi-marker linkage disequilibrium mapping of quantitative trait loci.Briefings in bioinformatics · 2017Article
- Constructing a linkage-linkage disequilibrium map using dominant-segregating markers.DNA research : an international journal for rapid publication of reports on genes and genomes · 2016Article
- Mapping complex traits as a dynamic system.Physics of life reviews · 2015Review
- Association and Validation of Yield-Favored Alleles in Chinese Cultivars of Common Wheat (Triticumaestivum L.).PloS one · 2015Article
- Bayesian model selection for multiple QTLs mapping combining linkage disequilibrium and linkage.Genetics research · 2014Article
- A combined linkage and regional association mapping validation and fine mapping of two major pleiotropic QTLs for seed weight and silique length in rapeseed (Brassica napus L.).BMC plant biology · 2014Article
- Genome-wide two-marker linkage disequilibrium mapping of quantitative trait loci.BMC genetics · 2014Article
- Genetic diversity and population structure in the US Upland cotton (Gossypium hirsutum L.).TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2014Article
- Dynamic semiparametric Bayesian models for genetic mapping of complex trait with irregular longitudinal data.Statistics in medicine · 2013Article
- Optimum design of family structure and allocation of resources in association mapping with lines from multiple crosses.Heredity · 2013Article
- Genetic mapping of complex traits by minimizing integrated square errors.BMC genetics · 2012Article
- Model and algorithm for linkage disequilibrium analysis in a non-equilibrium population.Frontiers in genetics · 2012Article
- Association mapping in an elite maize breeding population.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2011Article
- Systems mapping: how to improve the genetic mapping of complex traits through design principles of biological systems.BMC systems biology · 2011Article
- Joint linkage-linkage disequilibrium mapping is a powerful approach to detecting quantitative trait loci underlying drought tolerance in maize.Proceedings of the National Academy of Sciences of the United States of America · 2010Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Linkage analysis and allelic association (also referred to as linkage disequilibrium) studies are two major approaches for mapping genes that control simple or complex traits in plants, animals, and humans. But these two approaches have limited utility when used alone, because they use only part of the information that is available for a mapping population. More recently, a new mapping strategy has been designed to integrate the advantages of linkage analysis and linkage disequilibrium analysis for genome mapping in outcrossing populations. The new strategy makes use of a random sample from a panmictic population and the open-pollinated progeny of the sample. In this article, we extend the new strategy to map quantitative trait loci (QTL), using molecular markers within the EM-implemented maximum-likelihood framework. The most significant advantage of this extension is that both linkage and linkage disequilibrium between a marker and QTL can be estimated simultaneously, thus increasing the efficiency and effectiveness of genome mapping for recalcitrant outcrossing species. Simulation studies are performed to test the statistical properties of the MLEs of genetic and genomic parameters including QTL allele frequency, QTL effects, QTL position, and the linkage disequilibrium of the QTL and a marker. The potential utility of our mapping strategy is discussed.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.