ArticleGenetics2002
Cytogenetic analysis of the third chromosome heterochromatin of Drosophila melanogaster.
Article in Genetics, 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 15 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
15 citing papers in PubMed, 63 citations in OpenAlex.
- The Green Valley ofCells · 2022Review
- Characterization ofCells · 2022Article
- Genetic and Molecular Analysis of Essential Genes in Centromeric Heterochromatin of the Left Arm of Chromosome 3 inG3 (Bethesda, Md.) · 2019Article
- Islands of retroelements are major components of Drosophila centromeres.PLoS biology · 2019Article
- Simple and Complex Centromeric Satellites inGenetics · 2018Article
- A Short History and Description ofGenetics · 2017Article
- Article
- Mapping the pericentric heterochromatin by comparative genomic hybridization analysis and chromosome deletions in Drosophila melanogaster.Genome research · 2012Article
- Imaginal discs--a new source of chromosomes for genome mapping of the yellow fever mosquito Aedes aegypti.PLoS neglected tropical diseases · 2011Article
- Review
- High-resolution analysis of Drosophila heterochromatin organization using SuUR Su(var)3-9 double mutants.Proceedings of the National Academy of Sciences of the United States of America · 2007Article
- Cytogenetic and molecular characterization of heterochromatin gene models in Drosophila melanogaster.Genetics · 2007Article
- A genetic and molecular characterization of two proximal heterochromatic genes on chromosome 3 of Drosophila melanogaster.Genetics · 2005Article
- FISH analysis of Drosophila melanogaster heterochromatin using BACs and P elements.Chromosoma · 2003Article
- Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.Genome biology · 2002Article
Corrections and comments
- Erratum issued
Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Previous cytological analysis of heterochromatic rearrangements has yielded significant insight into the location and genetic organization of genes mapping to the heterochromatin of chromosomes X, Y, and 2 of Drosophila melanogaster. These studies have greatly facilitated our understanding of the genetic organization of heterochromatic genes. In contrast, the 12 essential genes known to exist within the mitotic heterochromatin of chromosome 3 have remained only imprecisely mapped. As a further step toward establishing a complete map of the heterochomatic genetic functions in Drosophila, we have characterized several rearrangements of chromosome 3 by using banding techniques at the level of mitotic chromosome. Most of the rearrangement breakpoints were located in the dull fluorescent regions h49, h51, and h58, suggesting that these regions correspond to heterochromatic hotspots for rearrangements. We were able to construct a detailed cytogenetic map of chromosome 3 heterochromatin that includes all of the known vital genes. At least 7 genes of the left arm (from l(3)80Fd to l(3)80Fj) map to segment h49-h51, while the most distal genes (from l(3)80Fa to l(3)80Fc) lie within the h47-h49 portion. The two right arm essential genes, l(3)81Fa and l(3)81Fb, are both located within the distal h58 segment. Intriguingly, a major part of chromosome 3 heterochromatin was found to be "empty," in that it did not contain either known genes or known satellite DNAs.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.