ArticleGenetics2002
Patterns of genetic variation at a chromosome 4 locus of Drosophila melanogaster and D. simulans.
Article in Genetics, 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
37 citing papers in PubMed, 77 citations in OpenAlex.
- Bait-ER: A Bayesian method to detect targets of selection in Evolve-and-Resequence experiments.Journal of evolutionary biology · 2023Article
- Sex Chromosome Evolution in Muscid Flies.G3 (Bethesda, Md.) · 2020Article
- Support for the Dominance Theory inGenetics · 2018Article
- Nucleotide diversity inflation as a genome-wide response to experimental lifespan extension in Drosophila melanogaster.BMC genomics · 2017Article
- Article
- Introgression maintains the genetic integrity of the mating-type determining chromosome of the fungus Neurospora tetrasperma.Genome research · 2016Article
- Rapid evolution of the intersexual genetic correlation for fitness in Drosophila melanogaster.Evolution; international journal of organic evolution · 2016Article
- Ancestral Chromatin Configuration Constrains Chromatin Evolution on Differentiating Sex Chromosomes in Drosophila.PLoS genetics · 2015Article
- The relation between recombination rate and patterns of molecular evolution and variation in Drosophila melanogaster.Molecular biology and evolution · 2014Article
- Recent selection on the Y-to-dot translocation in Drosophila pseudoobscura.Molecular biology and evolution · 2014Article
- Review
- The many landscapes of recombination in Drosophila melanogaster.PLoS genetics · 2012Article
- Sequencing of pooled DNA samples (Pool-Seq) uncovers complex dynamics of transposable element insertions in Drosophila melanogaster.PLoS genetics · 2012Article
- Chromosome-wide linkage disequilibrium caused by an inversion polymorphism in the white-throated sparrow (Zonotrichia albicollis).Heredity · 2011Article
- Reduced polymorphism associated with X chromosome meiotic drive in the stalk-eyed fly Teleopsis dalmanni.PloS one · 2011Article
- Recombination yet inefficient selection along the Drosophila melanogaster subgroup's fourth chromosome.Molecular biology and evolution · 2010Article
- Elevated levels of expression associated with regions of the Drosophila genome that lack crossing over.Biology letters · 2008Article
- Fine-scale mapping of recombination rate in Drosophila refines its correlation to diversity and divergence.Proceedings of the National Academy of Sciences of the United States of America · 2008Article
- High DNA sequence diversity in pericentromeric genes of the plant Arabidopsis lyrata.Genetics · 2008Article
- Hitchhiking effects of recurrent beneficial amino acid substitutions in the Drosophila melanogaster genome.Genome research · 2007Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
DNA sequence surveys of Drosophila melanogaster populations show a strong positive correlation between the recombination rate experienced by a locus and its level of nucleotide polymorphism. In particular, surveys of the fourth chromosome gene ci(D) show greatly reduced levels of nucleotide variation; this observation was originally interpreted in terms of selective sweeps occurring on the nonrecombining fourth chromosome. Subsequent theoretical work has, however, uncovered several other selective processes that can reduce variation. In this study, we revisit the Drosophila fourth chromosome, investigating variation in 5-6 kb of the gene ankyrin in D. melanogaster and D. simulans. Silent nucleotide site diversity is approximately 5 x 10(-4) for both species, consistent with the previous observations of low variation at ci(D). Given the observed frequency spectra at ankyrin, coalescent simulations indicate that reduced diversity in the region is unlikely to be due to a selective sweep alone. We find evidence for recombinational exchange at this locus, and both species appear to be fixed for an insertion of the transposable element HB in an intron of ankyrin.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.