Evidence map›Paper›PMID 11860208›Full record

ReviewPlant molecular biology2002

Gene replacement by homologous recombination in plants.

Holger Puchta

Open access · greenAbstract readReview
PubMed
In one paragraph

Review in Plant molecular biology, 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed
24.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 132 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Endodormancy Release Can Be Modulated by the GAFrontiers in plant science · 2021
    Article
  6. Article
  7. Article
  8. Homology-Directed Repair of a DefectiveFrontiers in plant science · 2018
    Article
  9. Review
  10. A review on advanced methods in plant gene targeting.Journal, genetic engineering & biotechnology · 2017
    Review
  11. Article
  12. Article
  13. Article
  14. Review
  15. Review
  16. Review
  17. Article
  18. Article
  19. Precise marker excision system using an animal-derived piggyBac transposon in plants.The Plant journal : for cell and molecular biology · 2014
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Holger PuchtaInstitut fur Pflanzengenetik und Kulturpflanzenforschung, Gatersleben, Germany. puchta@ipk-gatersleben.de
Leibniz Institute of Plant Genetics and Crop Plant Research · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

After the elucidation of the sequence of the yeast genome a major effort was started to elucidate the biological function of all open reading frames of this organisms by targeted gene replacement via homologous recombination. The establishment of the complete sequence of the genome of Arabidopsis thaliana would principally allow a similar approach. However, over the past dozen years all attempts to establish an efficient gene targeting technique in flowering plants were in the end not successful. In contrast, in Physcomitrella patens an efficient gene targeting procedure has been set up, making the moss a valuable model system for plant molecular biologists. But also for flowering plants recently several new approaches--some of them based on the availability of the genomic sequence of Arabidopsis--were initiated that might finally result on the set up of a general applicable technique. Beside the production of hyper-recombinogenic plants either via expression or suppression of specific gene functions or via undirected mutagenesis, the application of chimeric oligonucleotides might result in major progress.

Indexed as

Recombination, GeneticArabidopsisGenes, PlantGene TargetingPlants

Identifiers

PMID11860208
OpenAlexW2113568720

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.