ReviewPlant molecular biology2002
Metabolomics--the link between genotypes and phenotypes.
Review in Plant molecular biology, 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1,325 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1,325 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Metabolomic alterations in follicular fluid across female infertility conditions in IVF: a systematic review.Journal of assisted reproduction and genetics · 2026Pooled it
- Physical Activity and Metabolic Alterations in Children and Adolescents Across Different Weight Groups: A Systematic Review.European journal of sport science · 2026Pooled it
- Lipidomics in Periodontal Disease Research: A Systematic Review.Current medicinal chemistry · 2025Pooled it
- Metabolomic profiling of intensity-dependent responses to acute exercise in healthy humans.Journal of translational medicine · 2026Trial
- Metabolic reprogramming in plant defense: linking signaling networks to metabolomics-driven insights.Plant signaling & behavior · 2026Review
- Lifetime non-relational traumatic experiences are associated with biological ageing.GeroScience · 2026Article
- Integrating longitudinal metabolite profiles improves phenotype prediction in pigs in a trait- and timepoint-dependent manner.Genetics, selection, evolution : GSE · 2026Article
- Natural selection shapes the evolution of the metabolome in Saccharomyces cerevisiae.Molecular biology and evolution · 2026Article
- Metabonaut: an open educational resource for learning reproducible, script-based untargeted LC-MS/MS metabolomics.Metabolomics : Official journal of the Metabolomic Society · 2026Review
- The FERM guild: a differentially correlated microbial module drives hypertension via metabolic flux perturbations.mSystems · 2026Article
- Urinary metabolomics may improve prediction of overall survival beyond tumor stage in colorectal cancer: results from the ColoCare study.Metabolomics : Official journal of the Metabolomic Society · 2026Article
- Article
- Nanotechnology for sustainable agriculture: advances, applications and emerging role of multiomics.World journal of microbiology & biotechnology · 2026Review
- Chemical Ontogeny in Plants: Developmental Dynamics of Specialized Metabolism and Implications for Ecology, Quality Control, and Bioprospecting.Plants (Basel, Switzerland) · 2026Review
- A Metabolome Atlas of Grape Biodiversity.Journal of agricultural and food chemistry · 2026Article
- Long-Term Selection with α-Solanine Enhances Tolerance and Drives Multilevel Physiological Remodeling inInsects · 2026Article
- Metabolomics Reveals Flavonoid Profiles and Metabolite-Based Chemotypes in Plum (Foods (Basel, Switzerland) · 2026Article
- Organ-Resolved Untargeted LC-MS/MS Profiling of Putative Metabolite Families in Aerial Organs ofMetabolites · 2026Article
- Postmortem metabolomics as a window into the agonal phase of death: a comparison between opioid intoxications and hangings.International journal of legal medicine · 2026Article
- Article
1,265 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Metabolites are the end products of cellular regulatory processes, and their levels can be regarded as the ultimate response of biological systems to genetic or environmental changes. In parallel to the terms 'transcriptome' and proteome', the set of metabolites synthesized by a biological system constitute its 'metabolome'. Yet, unlike other functional genomics approaches, the unbiased simultaneous identification and quantification of plant metabolomes has been largely neglected. Until recently, most analyses were restricted to profiling selected classes of compounds, or to fingerprinting metabolic changes without sufficient analytical resolution to determine metabolite levels and identities individually. As a prerequisite for metabolomic analysis, careful consideration of the methods employed for tissue extraction, sample preparation, data acquisition, and data mining must be taken. In this review, the differences among metabolite target analysis, metabolite profiling, and metabolic fingerprinting are clarified, and terms are defined. Current approaches are examined, and potential applications are summarized with a special emphasis on data mining and mathematical modelling of metabolism.
Indexed as
Identifiers
11860207What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.