ArticleInfection and immunity2002
Influence of the alternative sigma(28) factor on virulence and flagellum expression of Legionella pneumophila.
Article in Infection and immunity, 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
29 citing papers in PubMed, 70 citations in OpenAlex.
- Ecology ofBiofilm · 2024Review
- Identification and Characterization of the Alternative σJournal of bacteriology · 2022Article
- New Global Insights on the Regulation of the Biphasic Life Cycle and Virulence Via ClpP-Dependent Proteolysis in Legionella pneumophila.Molecular & cellular proteomics : MCP · 2022Article
- The Life Cycle ofFrontiers in cellular and infection microbiology · 2018Review
- Factors Mediating Environmental Biofilm Formation byFrontiers in cellular and infection microbiology · 2018Review
- Disulfide loop cleavage of Legionella pneumophila PlaA boosts lysophospholipase A activity.Scientific reports · 2017Article
- Functional Analysis of the Alternative Sigma-28 Factor FliA and Its Anti-Sigma Factor FlgM of the Nonflagellated Legionella Species L. oakridgensis.Journal of bacteriology · 2017Article
- The Flagellar Regulon ofFrontiers in cellular and infection microbiology · 2017Review
- Amino Acid Uptake and Metabolism of Legionella pneumophila Hosted by Acanthamoeba castellanii.The Journal of biological chemistry · 2014Article
- The many forms of a pleomorphic bacterial pathogen-the developmental network of Legionella pneumophila.Frontiers in microbiology · 2014Review
- Innate immunity to Legionella and toll-like receptors - review.Folia microbiologica · 2010Review
- Isotopologue profiling of Legionella pneumophila: role of serine and glucose as carbon substrates.The Journal of biological chemistry · 2010Article
- ppGpp conjures bacterial virulence.Microbiology and molecular biology reviews : MMBR · 2010Review
- Distinct roles of ppGpp and DksA in Legionella pneumophila differentiation.Molecular microbiology · 2010Article
- Control of flagellar gene regulation in Legionella pneumophila and its relation to growth phase.Journal of bacteriology · 2010Article
- Two small ncRNAs jointly govern virulence and transmission in Legionella pneumophila.Molecular microbiology · 2009Article
- The Legionella autoinducer synthase LqsA produces an alpha-hydroxyketone signaling molecule.The Journal of biological chemistry · 2008Article
- Cytosolic recognition of flagellin by mouse macrophages restricts Legionella pneumophila infection.The Journal of experimental medicine · 2006Article
- Planktonic replication is essential for biofilm formation by Legionella pneumophila in a complex medium under static and dynamic flow conditions.Applied and environmental microbiology · 2006Article
- lbtA and lbtB are required for production of the Legionella pneumophila siderophore legiobactin.Journal of bacteriology · 2006Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The fliA gene of Legionella pneumophila encoding the alternative sigma(28) factor was inactivated by introducing a kanamycin resistance cassette. Electron microscopy and Western blot analysis revealed that the fliA mutant strain is aflagellate and expresses no flagellin. Reporter gene assays indicated that the flaA promoter is not active in the fliA mutant strain. The fliA mutant strain multiplied less effectively in coculture with amoebae than the wild-type strain and was not able to replicate in coculture with Dictyostelium discoideum.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.