ArticleInfection and immunity2002
Babesia bovis merozoite surface antigen 1 and rhoptry-associated protein 1 are expressed in sporozoites, and specific antibodies inhibit sporozoite attachment to erythrocytes.
Article in Infection and immunity, 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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Who cites it
26 citing papers in PubMed.
- Developing Anti-International journal of molecular sciences · 2023Review
- Advances inPathogens (Basel, Switzerland) · 2023Review
- Thrombospondin-Related Anonymous Protein (TRAP) Family Expression byMicroorganisms · 2022Article
- Comparative single-cell transcriptional atlases of Babesia species reveal conserved and species-specific expression profiles.PLoS biology · 2022Article
- Comparison of high throughput RNA sequences betweenFrontiers in cellular and infection microbiology · 2022Article
- Article
- Establishment ofPathogens (Basel, Switzerland) · 2021Article
- Characterization of the variable merozoite surface antigen (VMSA) gene family of Babesia orientalis.Parasitology research · 2020Article
- Innovative Alternatives for ContinuousPathogens (Basel, Switzerland) · 2020Article
- Variable and Variant Protein Multigene Families inPathogens (Basel, Switzerland) · 2019Review
- Molecular characterization of South Indian field isolates of bovine Babesia spp. and Anaplasma spp.Parasitology research · 2019Article
- Immunomolecular Characterization of MIC-1, a Novel Antigen in Babesia bigemina, Which Contains Conserved and Immunodominant B-Cell Epitopes that Induce Neutralizing Antibodies.Veterinary sciences · 2018Article
- Evaluation of a Major Surface Antigen ofFrontiers in microbiology · 2017Article
- A recombinant multi-antigen vaccine formulation containing Babesia bovis merozoite surface antigens MSA-2aParasites & vectors · 2016Article
- Expression analysis and biological characterization of Babesia sp. BQ1 (Lintan) (Babesia motasi-like) rhoptry-associated protein 1 and its potential use in serodiagnosis via ELISA.Parasites & vectors · 2016Article
- Transmission and epidemiology of zoonotic protozoal diseases of companion animals.Clinical microbiology reviews · 2013Review
- The invasion process of bovine erythrocyte by Babesia divergens: knowledge from an in vitro assay.Veterinary research · 2011Article
- Transovarial transmission efficiency of Babesia bovis tick stages acquired by Rhipicephalus (Boophilus) microplus during acute infection.Journal of clinical microbiology · 2007Article
- The Babesia bovis merozoite surface antigen 1 hypervariable region induces surface-reactive antibodies that block merozoite invasion.Infection and immunity · 2006Article
- Merozoite surface antigen 2 proteins of Babesia bovis vaccine breakthrough isolates contain a unique hypervariable region composed of degenerate repeats.Infection and immunity · 2005Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We examined Babesia bovis sporozoites for the expression of two molecules, merozoite surface antigen 1 (MSA-1) and rhoptry-associated protein 1 (RAP-1), that are postulated to be involved in the invasion of host erythrocytes. Both MSA-1 and RAP-1 were transcribed and expressed in infectious sporozoites. Importantly, monospecific MSA-1 and RAP-1 antisera each inhibited sporozoite invasion of erythrocytes in vitro. This is the first identification of antigens expressed in Babesia sp. sporozoites and establishes that, at least in part, sporozoites and merozoites share common targets of antibody mediated inhibition of erythrocyte invasion.
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