ArticleAntimicrobial agents and chemotherapy2002
Ribosomal mutations in Streptococcus pneumoniae clinical isolates.
Article in Antimicrobial agents and chemotherapy, 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.
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Who cites it
27 citing papers in PubMed, 1 synthesis or guideline pooled it, 60 citations in OpenAlex.
- Antimicrobial treatment guidelines for acute bacterial rhinosinusitis.Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery · 2004Guideline
- Tetracycline, Macrolide and Lincosamide Resistance inAntibiotics (Basel, Switzerland) · 2022Article
- Expanding the Scope of Protein Synthesis Using Modified Ribosomes.Journal of the American Chemical Society · 2019Article
- Clinical and Molecular Evidence of Atovaquone and Azithromycin Resistance in Relapsed Babesia microti Infection Associated With Rituximab and Chronic Lymphocytic Leukemia.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2017Article
- The macrolide antibiotic renaissance.British journal of pharmacology · 2017Review
- Resistance to Macrolide Antibiotics in Public Health Pathogens.Cold Spring Harbor perspectives in medicine · 2016Review
- A global map of genetic diversity in Babesia microti reveals strong population structure and identifies variants associated with clinical relapse.Nature microbiology · 2016Article
- Detection of the efflux-mediated erythromycin resistance transposon in Streptococcus pneumoniae.Annals of laboratory medicine · 2015Article
- Evidence of a conjugal erythromycin resistance element in the Lyme disease spirochete Borrelia burgdorferi.International journal of antimicrobial agents · 2007Article
- High-level telithromycin resistance in a clinical isolate of Streptococcus pneumoniae.Antimicrobial agents and chemotherapy · 2007Article
- Prevalence and molecular genetics of macrolide resistance among Streptococcus pneumoniae isolates collected in Finland in 2002.Antimicrobial agents and chemotherapy · 2005Article
- Predominance of 23S rRNA mutants among non-erm, non-mef macrolide-resistant clinical isolates of Streptococcus pneumoniae collected in the United States in 1999-2000.Antimicrobial agents and chemotherapy · 2005Article
- Antimicrobial susceptibility of Streptococcus pneumoniae in eight European countries from 2001 to 2003.Antimicrobial agents and chemotherapy · 2005Article
- Detection and quantification of macrolide resistance mutations at positions 2058 and 2059 of the 23S rRNA gene by pyrosequencing.Antimicrobial agents and chemotherapy · 2005Article
- Characterization of ermB gene transposition by Tn1545 and Tn917 in macrolide-resistant Streptococcus pneumoniae isolates.Journal of clinical microbiology · 2005Article
- In vitro activities of telithromycin, linezolid, and quinupristin-dalfopristin against Streptococcus pneumoniae with macrolide resistance due to ribosomal mutations.Antimicrobial agents and chemotherapy · 2004Article
- Mutation at the position 2058 of the 23S rRNA as a cause of macrolide resistance in Streptococcus pyogenes.Annals of clinical microbiology and antimicrobials · 2004Article
- Alterations at the peptidyl transferase centre of the ribosome induced by the synergistic action of the streptogramins dalfopristin and quinupristin.BMC biology · 2004Article
- Mutations in a 23S rRNA gene of Chlamydia trachomatis associated with resistance to macrolides.Antimicrobial agents and chemotherapy · 2004Article
- Ribosomal mutations in Arcanobacterium pyogenes confer a unique spectrum of macrolide resistance.Antimicrobial agents and chemotherapy · 2004Article
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Eleven clinical isolates of Streptococcus pneumoniae, isolated in Finland during 1996 to 2000, had an unusual macrolide resistance phenotype. They were resistant to macrolides and streptogramin B but susceptible, intermediate, or low-level resistant to lincosamides. No acquired macrolide resistance genes were detected from the strains. The isolates were found to have mutations in domain V of the 23S rRNA or ribosomal protein L4. Seven isolates had an A2059C mutation in two to four out of the four alleles encoding the 23S rRNA, two isolates had an A2059G mutation in two alleles, one isolate had a C2611G mutation in all four alleles, and one isolate had a 69GTG71-to-69TPS71 substitution in ribosomal protein L4.
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Registered trials
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