ArticleBritish journal of clinical pharmacology2002
Statins and the risk of idiopathic venous thromboembolism.
Article in British journal of clinical pharmacology, 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 5 of them syntheses that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
21 citing papers in PubMed, 5 syntheses or guidelines pooled it.
- Statins for the primary prevention of venous thromboembolism.The Cochrane database of systematic reviews · 2024Pooled it
- Statins for primary prevention of venous thromboembolism.The Cochrane database of systematic reviews · 2014Pooled it
- Unintended effects of statins from observational studies in the general population: systematic review and meta-analysis.BMC medicine · 2014 · on this mapPooled it
- Guideline
- Validation and validity of diagnoses in the General Practice Research Database: a systematic review.British journal of clinical pharmacology · 2010Pooled it
- Statins, aspirin and risk of venous thromboembolic events in breast cancer patients.Journal of thrombosis and thrombolysis · 2014Trial
- Incident venous thromboembolic events in the Prospective Study of Pravastatin in the Elderly at Risk (PROSPER).BMC geriatrics · 2011Trial
- A randomized trial of rosuvastatin in the prevention of venous thromboembolism.The New England journal of medicine · 2009 · on this mapTrial
- Risk of Venous Thromboembolism in Statin Users Compared to Fibrate Users in the United Kingdom Clinical Practice Research Datalink (UK CPRD) GOLD.Clinical epidemiology · 2024Article
- Statins and Venous Thromboembolic Disease - Where are we Now?Current vascular pharmacology · 2024Review
- Risk of Venous Thromboembolism with Statins: Evidence Gathered via a Network Meta-analysisBalkan medical journal · 2023Article
- Statins can benefit patients with primary membranous nephropathy on venous thromboembolism.Renal failure · 2021Article
- How to validate a diagnosis recorded in electronic health records.Breathe (Sheffield, England) · 2019Article
- Is lipid lowering therapy an independent risk factor for venous thromboembolism? A population-based case-control study.Thrombosis research · 2015Article
- Influence of statin use on the incidence of recurrent venous thromboembolism and major bleeding in patients receiving rivaroxaban or standard anticoagulant therapy.Thrombosis journal · 2014Article
- The association between statin therapy during intensive care unit stay and the incidence of venous thromboembolism: a propensity score-adjusted analysis.BMC pharmacology & toxicology · 2013Observational
- Sources of tissue factor that contribute to thrombosis after rupture of an atherosclerotic plaque.Thrombosis research · 2012Review
- Effect of statins on a wide range of health outcomes: a cohort study validated by comparison with randomized trials.British journal of clinical pharmacology · 2009Article
- Statins and the risk of idiopathic venous thromboembolism.British journal of clinical pharmacology · 2003Article
- Who receives lipid-lowering drugs: the effects of comorbidities and patient characteristics on treatment initiation.British journal of clinical pharmacology · 2003Article
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimsTo evaluate the association between current statin use and the risk of idiopathic venous thromboembolism (VTE).
methodsA population-based retrospective follow-up with a nested case-control analysis using the General Practice Research Database.
resultsThere were 72 cases of idiopathic VTE. Using normolipidaemic nonuse as the reference group, the adjusted relative risks for idiopathic VTE for current/recent statin use, past statin use, past other lipid-lowering drug use, and hyperlipidaemic nonuse were 0.8 (0.3, 2.7), 2.4 (0.6, 10.0), 1.8 (0.4, 7.4), and 0.9 (0.4, 2.0) in the follow-up analysis, and were 1.1 (0.3, 4.3), 3.7 (0.6, 24.1), 2.0 (0.3, 11.6), and 0.4 (0.2, 1.2) in the case-control analysis.
conclusionsCurrent statin use was not associated with a reduced risk of idiopathic VTE.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.