ArticleHeart (British Cardiac Society)2002
Left ventricular diastolic function assessed using Doppler tissue imaging in patients with hypertrophic cardiomyopathy: relation to symptoms and exercise capacity.
Article in Heart (British Cardiac Society), 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
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33 citing papers in PubMed, 180 citations in OpenAlex.
- Association of left ventricular global area strain derived from resting 3D speckle-tracking echocardiography and exercise capacity in individuals undergoing treadmill exercise test.International journal of medical sciences · 2022Article
- Cardiopulmonary Exercise Test in Patients with Hypertrophic Cardiomyopathy: A Systematic Review and Meta-Analysis.Journal of clinical medicine · 2021Review
- Hypertrophic Cardiomyopathy: Updates Through the Lens of Sports Cardiology.Current treatment options in cardiovascular medicine · 2021Review
- Exercise and hypertrophic cardiomyopathy: Two incompatible entities?Clinical cardiology · 2020Review
- Cardiac Imaging in the Athlete: Shrinking the "Gray Zone".Current treatment options in cardiovascular medicine · 2020Review
- Exploring the Continuum of Hypertrophic Cardiomyopathy-From DNA to Clinical Expression.Medicina (Kaunas, Lithuania) · 2019Review
- Predictors of Exercise Capacity in Patients with Hypertrophic Obstructive Cardiomyopathy.Journal of clinical medicine · 2018Article
- Comparison of echocardiography with tissue Doppler imaging and magnetic resonance imaging with delayed enhancement in the assessment of children with hypertrophic cardiomyopathy.Archives of medical science : AMS · 2017Article
- Myocardial energy depletion and dynamic systolic dysfunction in hypertrophic cardiomyopathy.Nature reviews. Cardiology · 2016Review
- Echocardiographic diagnosis of the different phenotypes of hypertrophic cardiomyopathy.Cardiovascular ultrasound · 2016Review
- The association between brain natriuretic peptide and tissue Doppler parameters in children with hypertrophic cardiomyopathy.Bosnian journal of basic medical sciences · 2016Article
- The presence and impact of diastolic dysfunction on physical function and body composition in hemodialysis patients.Journal of nephrology · 2015Article
- Echocardiography in the evaluation of athletes.F1000Research · 2015Review
- The role of new echocardiographic techniques in athlete's heart.F1000Research · 2015Review
- Association of noninvasively measured left ventricular mechanics with in vitro muscle contractile performance: a prospective study in hypertrophic cardiomyopathy patients.Journal of the American Heart Association · 2014Article
- Normal electrocardiographic and echocardiographic (M-mode and two-dimensional) values in Polish Landrace pigs.Acta veterinaria Scandinavica · 2014Article
- Reduction of left ventricular longitudinal global and segmental systolic functions in patients with hypertrophic cardiomyopathy: Study of two-dimensional tissue motion annular displacement.Experimental and therapeutic medicine · 2014Article
- Determinants of peak oxygen uptake in patients with hypertrophic cardiomyopathy: a single-center study.Internal and emergency medicine · 2014Article
- Article
- Silencing of the Drosophila ortholog of SOX5 in heart leads to cardiac dysfunction as detected by optical coherence tomography.Human molecular genetics · 2013Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundConventional Doppler indices of left ventricular diastolic function do not correlate with symptoms or exercise capacity in patients with hypertrophic cardiomyopathy, because of their dependence on loading conditions. Diastolic mitral annular velocity measured using Doppler tissue imaging has been reported to be a preload independent index of left ventricular diastolic function.
objectiveTo determine the relation between diastolic annular velocities combined with conventional Doppler indices and symptoms or exercise capacity in hypertrophic cardiomyopathy.
methods85 patients with hypertrophic cardiomyopathy and 60 normal controls were studied. Diastolic mitral annular velocities, transmitral left ventricular filling, and pulmonary venous velocities were measured.
resultsEarly diastolic velocities at lateral and septal annulus were lower in patients with hypertrophic cardiomyopathy than in controls (lateral Ea: 10 (3) v 18 (4) cm/s, p < 0.0001; septal Ea: 7 (2) v 12 (3) cm/s, p < 0.0001). Unlike conventional Doppler indices alone, transmitral early left ventricular filling velocity (E) to lateral Ea ratio correlated inversely with peak oxygen consumption (r = -0.42, p < 0.0001). Patients in New York Heart Association (NYHA) class III had a higher transmitral E to lateral Ea ratio (12.0 (4.6)) than those in NYHA class II (7.6 (3.1), p < 0.005) or class I (6.6 (2.6), p < 0.0001).
conclusionsEarly diastolic mitral annular velocities are reduced in patients with hypertrophic cardiomyopathy. Unlike conventional Doppler indices alone, the transmitral E to lateral Ea ratio correlates with NYHA functional class and exercise capacity.
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