Evidence map›Paper›PMID 11844778›Full record

ArticleJournal of bacteriology2002

Bypass of A- and B-signaling requirements for Myxococcus xanthus development by mutations in spdR.

Hubert Tse, Ronald E Gill

Abstract read
In one paragraph

Article in Journal of bacteriology, 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Hubert TseDepartment of Microbiology, University of Colorado Health Sciences Center, 4200 E. Ninth Street, Denver, CO 80262, USA.
Ronald E Gill

Funding

REGULATION OF GENE EXPRESSION BY CELL-CELL INTERACTIONSR01GM031900 · NIGMS · UNIVERSITY OF COLORADO DENVER · PI GILL, RONALD E · 1985 to 1995
–
NIGMS NIH HHS GM 31900
6 · The paper itself

Abstract

Mutations in spdR, previously reported to bypass the developmental requirement for B-signaling in Myxococcus xanthus, also bypass the requirement for A-signaling but not C-, D-, or E-signaling. Mutations in spdR restored nearly wild-type levels of sporulation to representative A-signal-deficient mutants carrying asgA476, asgB480, and asgC767 and improved the quality of fruiting body formation in the asgB480 mutant. The defect in A-factor production by the asgB480 mutant was not restored in the spdR2134 asgB480 double mutant.

Indexed as

MutationTranscription Factors4-ButyrolactoneBacterial ProteinsEndopeptidasesGene Expression Regulation, BacterialMyxococcus xanthusSignal Transduction4-ButyrolactoneA-factor (Streptomyces)Bacterial ProteinsBsgA protein, Myxococcus xanthusEndopeptidasesSpdR protein, Myxococcus xanthusTranscription Factors

Identifiers

PMID11844778
PMCPMC134832

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.