ArticleProceedings of the National Academy of Sciences of the United States of America2002
Long-term microclimatic stress causes rapid adaptive radiation of kaiABC clock gene family in a cyanobacterium, Nostoc linckia, from "Evolution Canyons" I and II, Israel.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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12 citing papers in PubMed, 49 citations in OpenAlex.
- Homologs of Circadian Clock Proteins Impact the Metabolic Switch Between Light and Dark Growth in the CyanobacteriumFrontiers in plant science · 2021Article
- Evaluating evolutionary models of stress-induced mutagenesis in bacteria.Nature reviews. Genetics · 2013Review
- Patterns of nucleotide diversity of the ldpA circadian gene in closely related species of cyanobacteria from extreme cold deserts.Applied and environmental microbiology · 2013Article
- RNA-seq based identification and mutant validation of gene targets related to ethanol resistance in cyanobacterial Synechocystis sp. PCC 6803.Biotechnology for biofuels · 2012Article
- Extreme conservation and non-neutral evolution of the cpmA Circadian locus in a globally distributed Chroococcidiopsis sp. from naturally stressful habitats.Molecular biology and evolution · 2012Article
- Positive selection of co-opted mobile genetic elements in a mammalian gene: If you can't beat them, join them.Mobile genetic elements · 2012Article
- "Evolution Canyon," a potential microscale monitor of global warming across life.Proceedings of the National Academy of Sciences of the United States of America · 2012Article
- Adaptation and incipient sympatric speciation of Bacillus simplex under microclimatic contrast at "Evolution Canyons" I and II, Israel.Proceedings of the National Academy of Sciences of the United States of America · 2005Article
- Stress-induced variation in evolution: from behavioural plasticity to genetic assimilation.Proceedings. Biological sciences · 2005Review
- Molecular evolution of ldpA, a gene mediating the circadian input signal in cyanobacteria.Journal of molecular evolution · 2005Article
- Evidence for multiple lateral transfers of the circadian clock cluster in filamentous heterocystic cyanobacteria Nostocaceae.Journal of molecular evolution · 2004Article
- Origin and evolution of circadian clock genes in prokaryotes.Proceedings of the National Academy of Sciences of the United States of America · 2003Article
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3 authors at 2 institutions in 2 countries.
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Abstract
Cyanobacteria are the only prokaryotes known thus far possessing regulation of physiological functions with approximate daily periodicity, or circadian rhythms, that are controlled by a cluster of three genes, kaiA, kaiB, and kaiC. Here we demonstrate considerably higher genetic polymorphism and extremely rapid evolution of the kaiABC gene family in a filamentous cyanobacterium, Nostoc linckia, permanently exposed to the acute natural environmental stress in the two microsite evolutionary models known as "Evolution Canyons," I (Mount Carmel) and II (Upper Galilee) in Israel. The family consists of five distinct subfamilies (kaiI-kaiV) comprising at least 20 functional genes and pseudogenes. The obtained data suggest that the duplications of kai genes have adaptive significance, and some of them are evolutionarily quite recent (approximately 80,000 years ago). The observed patterns of within- and between-subfamily polymorphisms indicate that positive diversifying, balancing, and purifying selections are the principal driving forces of the kai gene family's evolution.
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