Trial reportJournal of general internal medicine2002
Barriers to initiating depression treatment in primary care practice.
Trial report in Journal of general internal medicine, 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 86 papers, 6 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
86 citing papers in PubMed, 6 syntheses or guidelines pooled it, 195 citations in OpenAlex.
- Clinical practice guidelines with recommendations for peripartum depression: A European systematic review.Acta psychiatrica Scandinavica · 2022Pooled it
- Pooled it
- Collaborative care for anxiety disorders in primary care: a systematic review and meta-analysis.BMC family practice · 2016Pooled it
- Collaborative care for depression and anxiety problems.The Cochrane database of systematic reviews · 2012Pooled it
- Facilitators and barriers to implementing quality measurement in primary mental health care: Systematic review.Canadian family physician Medecin de famille canadien · 2010Pooled it
- Psychotherapy mediated by remote communication technologies: a meta-analytic review.BMC psychiatry · 2008Pooled it
- Re-Engagement into Care: The Role of Social Support on Service Use for Recurrent Episodes of Mental Health Distress Among Primary Care Patients.The journal of behavioral health services & research · 2018Trial
- Role of magnesium supplementation in the treatment of depression: A randomized clinical trial.PloS one · 2017Trial
- 'One man's medicine is another man's poison': a qualitative study of user perspectives on low intensity interventions for Obsessive-Compulsive Disorder (OCD).BMC health services research · 2016Trial
- Psychosocial intervention improves depression, quality of life, and fluid adherence in hemodialysis.Journal of the American Society of Nephrology : JASN · 2014Trial
- Internal versus external motivation in referral of primary care patients with depression to an internet support group: randomized controlled trial.Journal of medical Internet research · 2013Trial
- Trial
- Patients and computers as reminders to screen for diabetes in family practice. Randomized-controlled trial.Journal of general internal medicine · 2005Trial
- The effect of improving primary care depression management on employee absenteeism and productivity. A randomized trial.Medical care · 2004Trial
- Re-engineering systems for the treatment of depression in primary care: cluster randomised controlled trial.BMJ (Clinical research ed.) · 2004Trial
- RCT of a care manager intervention for major depression in primary care: 2-year costs for patients with physical vs psychological complaints.Annals of family medicineTrial
- Going to scale: re-engineering systems for primary care treatment of depression.Annals of family medicineTrial
- Urgency to treat and early optimized treatment in major depressive disorder: consequences of delayed treatment, barriers to implementation, and practical strategies for clinicians.CNS spectrums · 2025Review
- Protocol of a randomized controlled trial of nurse-led de-stressful skill interventions in patients with depression disorder.Journal of education and health promotion · 2025Article
- Epidemiological features of depression and anxiety among homeless adults with healthcare access problems in London, UK: descriptive cross-sectional analysis.BJPsych open · 2024Article
26 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 2 institutions in 1 country.
Funding
Abstract
OBJECTIVE AND
designThis study used qualitative and quantitative methods to examine the reasons primary care physicians and nurses offered for their inability to initiate guideline-concordant acute-phase care for patients with current major depression. PARTICIPANTS AND
settingTwo hundred thirty-nine patients with 5 or more symptoms of depression seeing 12 physicians in 6 primary care practices were randomized to the intervention arm of a trial of the effectiveness of depression treatment. Sixty-six (27.6%) patients identified as failing to meet criteria for guideline-concordant treatment 8 weeks following the index visit were the focus of this analysis.
methodsThe research team interviewed the 12 physicians and 6 nurse care managers to explore the major reasons depressed patients fail to receive guideline-concordant acute-phase care. This information was used to develop a checklist of barriers to depression care. The 12 physicians then completed the checklist for each of the 64 patients for whom he or she was the primary care provider. Physicians chose which barriers they felt applied to each patient and weighted the importance of the barrier by assigning a total of 100 points for each patient. Cluster analysis of barrier scores identified naturally occurring groups of patients with common barrier profiles.
resultsThe cluster analysis produced a 5-cluster solution with profiles characterized by patient resistance (19 patients, 30.6%), patient noncompliance with visits (15 patients, 24.2%), physician judgment overruled the guideline (12 patients, 19.3%), patient psychosocial burden (8 patients, 12.9%), and health care system problems (8 patients, 12.9%). The physicians assigned 4,707 (75.9%) of the 6,200 weighting points to patient-centered barriers. Physician-centered barriers accounted for 927 (15.0%) and system barriers accounted for 566 (9.1%) of weighting points. Twenty-eight percent of the patients not initiating guideline-concordant acute-stage care went on to receive additional care and met criteria for remission at 6 months, with no statistical difference across the 5 patient clusters.
conclusionsCurrent interventions fail to address barriers to initiating guideline-concordant acute-stage care faced by more than a quarter of depressed primary care patients. Physicians feel that barriers arise most frequently from factors centered with the patients, their psychosocial circumstances, and their attitudes and beliefs about depression and its care. Physicians less frequently make judgments that overrule the guidelines, but do so when patients have complex illness patterns. Further descriptive and experimental studies are needed to confirm and further examine barriers to depression care. Because few untreated patients improve without acute-stage care, additional work is also needed to develop new intervention components that address these barriers.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.