ArticleOncogene2001
The regulation and function of the Id proteins in lymphocyte development.
Article in Oncogene, 2001. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
28 citing papers in PubMed, 80 citations in OpenAlex.
- ID2 Suppresses Multiple Myeloma Cell Proliferation by Repressing the Activity of the Transcription Factor TCF3.Blood cancer discovery · 2026Article
- Mechanisms of Binding Specificity among bHLH Transcription Factors.International journal of molecular sciences · 2021Review
- Single-cell RNA-sequencing identifies the developmental trajectory of C-Myc-dependent NK1.1Mucosal immunology · 2020Article
- The Transcriptional Regulator Id2 Is Critical for Adipose-Resident Regulatory T Cell Differentiation, Survival, and Function.Journal of immunology (Baltimore, Md. : 1950) · 2019Article
- BMP-SMAD-ID promotes reprogramming to pluripotency by inhibiting p16/INK4A-dependent senescence.Proceedings of the National Academy of Sciences of the United States of America · 2016Article
- Snai2 and Snai3 transcriptionally regulate cellular fitness and functionality of T cell lineages through distinct gene programs.Immunobiology · 2016Article
- Phosphorylation Regulates Id2 Degradation and Mediates the Proliferation of Neural Precursor Cells.Stem cells (Dayton, Ohio) · 2016Article
- Article
- Gene expression patterns in bone following lipopolysaccharide stimulation.Cellular & molecular biology letters · 2014Article
- Susceptibility of hepatoma-derived cells to histone deacetylase inhibitors is associated with ID2 expression.International journal of oncology · 2013Article
- A genome-wide regulatory network identifies key transcription factors for memory CD8⁺ T-cell development.Nature communications · 2013Article
- Differential modulation of the oligodendrocyte transcriptome by sonic hedgehog and bone morphogenetic protein 4 via opposing effects on histone acetylation.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2012Article
- Biochemical and phosphoproteomic analysis of the helix-loop-helix protein E47.Molecular and cellular biology · 2012Article
- The many roles of TOX in the immune system.Current opinion in immunology · 2012Review
- TOX is required for development of the CD4 T cell lineage gene program.Journal of immunology (Baltimore, Md. : 1950) · 2011Article
- Multilineage priming of enhancer repertoires precedes commitment to the B and myeloid cell lineages in hematopoietic progenitors.Immunity · 2011Article
- Stage-specific functions of E-proteins at the β-selection and T-cell receptor checkpoints during thymocyte development.Immunologic research · 2011Article
- Modeling Sjögren's syndrome with Id3 conditional knockout mice.Immunology letters · 2011Article
- Transcriptional regulator Id2 controls survival of hepatic NKT cells.Proceedings of the National Academy of Sciences of the United States of America · 2009Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Helix-loop-helix (HLH) proteins are essential factors for lymphocyte development and function. One class of HLH proteins, the E-proteins, regulate many aspects of lymphocyte maturation, survival, proliferation, and differentiation. E-proteins are negatively regulated by another class of HLH proteins known as the Id proteins. The Id proteins function as dominant negative inhibitors of E-proteins by inhibiting their ability to bind DNA. Here we discuss the function and regulation of the Id proteins in lymphocyte development.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.