ReviewEnvironmental health perspectives2002
Dichlorodiphenyltrichloroethane (DDT): ubiquity, persistence, and risks.
Review in Environmental health perspectives, 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 142 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
142 citing papers in PubMed, 5 syntheses or guidelines pooled it, 668 citations in OpenAlex.
- Assessment of ovarian dysfunction induced by environmental toxins: a systematic review.Frontiers in public health · 2025Pooled it
- A systematic review of poeciliid fish invasions in Africa.BMC ecology and evolution · 2024Pooled it
- Pooled it
- The classic EDCs, phthalate esters and organochlorines, in relation to abnormal sperm quality: a systematic review with meta-analysis.Scientific reports · 2016Pooled it
- Dichlorodiphenyldichloroethane burden and breast cancer risk: a meta-analysis of the epidemiologic evidence.Environmental health perspectives · 2004Pooled it
- Review
- Article
- Article
- Molspectra: a general framework for multi-spectra prediction from molecular structures.Journal of molecular modeling · 2026Article
- Toward "Safe" Chemicals and Materials on Mars: Knowledge Gaps for Expanding Planetary Protection Requirements.Environmental science & technology · 2026Review
- Assessing morphological, developmental, and genetic responses of Hydropsychid caddisflies to Cry1Ab exposure.Environmental entomology · 2026Article
- Reducing Close Encounters with Insect Pests and Vectors: The Past, Present and Future of Insect Repellents.Insects · 2026Review
- DDT exposure induces microglial activation and disease-associated microglial signatures: Relevance to mechanisms of Alzheimer's disease.Neurotoxicology · 2025Article
- Endocrine Disrupting Agents: Toxicological Aspects on Male Reproduction.Reproductive sciences (Thousand Oaks, Calif.) · 2025Review
- Catalyst-free photoinduced dehalogenation and functionalization of alkyl halides using Lewis bases.RSC advances · 2025Article
- Lifestyle and Environmental Factors Affecting Male Fertility, Individual Predisposition, Prevention, and Intervention.International journal of molecular sciences · 2025Review
- Potential effects of environmental toxicants on sperm quality and potential risk for fertility in humans.Frontiers in endocrinology · 2025Review
- Human-Caused High Direct Mortality in Birds: Unsustainable Trends and Ameliorative Actions.Animals : an open access journal from MDPI · 2024Article
- Pesticide pollution in India: Environmental and health risks, and policy challenges.Toxicology reports · 2024Article
- Insecticide Resistance inInsects · 2024Article
82 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Due to uncontrolled use for several decades, dichlorodiphenyltrichloroethane (DDT), probably the best known and most useful insecticide in the world, has damaged wildlife and might have negative effects on human health. This review gives a brief history of the use of DDT in various countries and presents the results of epidemiologic and experimental studies of carcinogenesis. Even though its use has been prohibited in most countries for ecologic considerations, mainly because of its negative impact on wildlife, it is still used in some developing countries for essential public health purposes, and it is still produced for export in at least three countries. Due to its stability and its capacity to accumulate in adipose tissue, it is found in human tissues, and there is now not a single living organism on the planet that does not contain DDT. The possible contribution of DDT to increasing the risks for cancers at various sites and its possible role as an endocrine disruptor deserve further investigation. Although there is convincing experimental evidence for the carcinogenicity of DDT and of its main metabolites DDE and DDD, epidemiologic studies have provided contrasting or inconclusive, although prevailingly negative, results. The presence and persistence of DDT and its metabolites worldwide are still problems of great relevance to public health. Efficient pesticides that do not have the negative properties of DDT, together with the development of alternative methods to fight malaria, should be sought with the goal of completely banning DDT.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.