ArticleHuman brain mapping2002
Isotropic resolution diffusion tensor imaging with whole brain acquisition in a clinically acceptable time.
Article in Human brain mapping, 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 65 papers.
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Who cites it
65 citing papers in PubMed, 181 citations in OpenAlex.
- Spatial and orientational heterogeneity in the statistical sensitivity of skeleton-based analyses of diffusion tensor MR imaging data.Journal of neuroscience methods · 2011Trial
- Structural integrity of the anterior thalamic radiation predicts alpha oscillations and inattention during visual encoding.Scientific reports · 2026Article
- Reproducibility of quantitative ADC, T1, and T2 measurement on the cerebral cortex: Utility of whole brain echo-planar DWI with compressed SENSE (EPICS-DWI): A pilot study.European journal of radiology open · 2023Article
- Article
- Evolution of white matter damage in amyotrophic lateral sclerosis.Annals of clinical and translational neurology · 2020Article
- Identification of neurobehavioural symptom groups based on shared brain mechanisms.Nature human behaviour · 2019Article
- Inter-hemispheric Asymmetry Patterns in the ADHD Brain: A Neuroimaging Replication Study.Proceedings of SPIE--the International Society for Optical Engineering · 2019Article
- Cervical Spine Prospective Feasibility Study : Dynamic Flexion-Extension Diffusion-Tensor Weighted Magnetic Resonance Imaging.Clinical neuroradiology · 2019Article
- Brain Peak Width of Skeletonized Mean Diffusivity (PSMD) and Cognitive Function in Later Life.Frontiers in psychiatry · 2019Article
- A Simplified Crossing Fiber Model in Diffusion Weighted Imaging.Frontiers in neuroscience · 2019Article
- Spatial Gradient of Microstructural Changes in Normal-Appearing White Matter in Tracts Affected by White Matter Hyperintensities in Older Age.Frontiers in neurology · 2019Article
- Mapping fine-scale anatomy of gray matter, white matter, and trigeminal-root region applying spherical deconvolution to high-resolution 7-T diffusion MRI.Magma (New York, N.Y.) · 2018Article
- Schizophrenia moderates the relationship between white matter integrity and cognition.Schizophrenia research · 2018Article
- Anatomy of the dorsal default-mode network in conduct disorder: Association with callous-unemotional traits.Developmental cognitive neuroscience · 2018Article
- The Relationship between Lesion Severity Characterized by Diffusion Tensor Imaging and Motor Function in Chronic Canine Spinal Cord Injury.Journal of neurotrauma · 2018Article
- Cognitive abilities, brain white matter hyperintensity volume, and structural network connectivity in older age.Human brain mapping · 2018Article
- White matter deficits in schizophrenia are global and don't progress with age.The Australian and New Zealand journal of psychiatry · 2017Article
- White matter alterations to cingulum and fornix following very preterm birth and their relationship with cognitive functions.NeuroImage · 2017Article
- Sex differences in frontal lobe connectivity in adults with autism spectrum conditions.Translational psychiatry · 2017Article
- Increased fractional anisotropy in the motor tracts of Parkinson's disease suggests compensatory neuroplasticity or selective neurodegeneration.European radiology · 2016Article
5 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
Abstract
Our objective was to develop a diffusion tensor MR imaging pulse sequence that allows whole brain coverage with isotropic resolution within a clinically acceptable time. A single-shot, cardiac-gated MR pulse sequence, optimized for measuring the diffusion tensor in human brain, was developed to provide whole-brain coverage with isotropic (2.5 x 2.5 x 2.5 mm) spatial resolution, within a total imaging time of approximately 15 min. The diffusion tensor was computed for each voxel in the whole volume and the data processed for visualization in three orthogonal planes. Anisotropy data were further visualized using a maximum-intensity projection algorithm. Finally, reconstruction of fiber-tract trajectories i.e., "tractography" was performed. Images obtained with this pulse sequence provide clear delineation of individual white matter tracts, from the most superior cortical regions down to the cerebellum and brain stem. Because the data are acquired with isotropic resolution, they can be reformatted in any plane and the sequence can therefore be used, in general, for macroscopic neurological or psychiatric neuroimaging investigations. The 3D visualization afforded by maximum intensity projection imaging and tractography provided easy visualization of individual white matter fasciculi, which may be important sites of neuropathological degeneration or abnormal brain development. This study has shown that it is possible to obtain robust, high quality diffusion tensor MR data at 1.5 Tesla with isotropic resolution (2.5 x 2.5 x 2.5 mm) from the whole brain within a sufficiently short imaging time that it may be incorporated into clinical imaging protocols.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.