ReviewNature2002
Plasmodium, human and Anopheles genomics and malaria.
Review in Nature, 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
30 citing papers in PubMed.
- Propulsive cell entry diverts pathogens from immune degradation by remodeling the phagocytic synapse.bioRxiv : the preprint server for biology · 2023Article
- Genetic approach towards a vaccine against malaria.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2018Review
- The potential of anti-malarial compounds derived from African medicinal plants, part III: an in silico evaluation of drug metabolism and pharmacokinetics profiling.Organic and medicinal chemistry letters · 2014Article
- An in vivo transfection approach elucidates a role for Aedes aegypti thioester-containing proteins in flaviviral infection.PloS one · 2011Article
- Post-genomic challenges for collaborative research in infectious diseases.Nature reviews. Microbiology · 2008Review
- Genomewide expression profiling of cryptolepine-induced toxicity in Saccharomyces cerevisiae.Antimicrobial agents and chemotherapy · 2008Article
- A novel GDP-dependent pyruvate kinase isozyme from Toxoplasma gondii localizes to both the apicoplast and the mitochondrion.The Journal of biological chemistry · 2008Article
- Amodiaquine failure associated with erythrocytic glutathione in Plasmodium falciparum malaria.Malaria journal · 2007Article
- Assembling a global database of malaria parasite prevalence for the Malaria Atlas Project.Malaria journal · 2007Review
- Identifying Plasmodium falciparum cytoadherence-linked asexual protein 3 (CLAG 3) sequences that specifically bind to C32 cells and erythrocytes.Protein science : a publication of the Protein Society · 2005Article
- The unusually large Plasmodium telomerase reverse-transcriptase localizes in a discrete compartment associated with the nucleolus.Nucleic acids research · 2005Article
- Detection of four Plasmodium species in blood from humans by 18S rRNA gene subunit-based and species-specific real-time PCR assays.Journal of clinical microbiology · 2004Article
- Cachexia in malaria and heart failure: therapeutic considerations in clinical practice.Postgraduate medical journal · 2004Review
- Cross-talk between nitric oxide and transforming growth factor-beta1 in malaria.Current molecular medicine · 2004Review
- High-throughput generation of P. falciparum functional molecules by recombinational cloning.Genome research · 2004Article
- Targeting enzymes involved in spermidine metabolism of parasitic protozoa--a possible new strategy for anti-parasitic treatment.Parasitology research · 2003Article
- Mammalian transforming growth factor beta1 activated after ingestion by Anopheles stephensi modulates mosquito immunity.Infection and immunity · 2003Article
- Malaria parasites solve the problem of a low calcium environment.The Journal of cell biology · 2003Review
- Identification and characterization of a conserved, stage-specific gene product of Plasmodium falciparum recognized by parasite growth inhibitory antibodies.Infection and immunity · 2003Article
- Construction of a BAC library and generation of BAC end sequence-tagged connectors for genome sequencing of the African malaria mosquito Anopheles gambiae.Molecular genetics and genomics : MGG · 2003Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The Plasmodium spp. parasites that cause malaria are transmitted to humans by Anopheles spp. mosquitoes. Scientists have now amassed a great body of knowledge about the parasite, its mosquito vector and human host. Yet this year there will be 300-500 million new malaria infections and 1-3 million deaths caused by the disease. We believe that integrated analyses of genome sequence, DNA polymorphisms, and messenger RNA and protein expression profiles will lead to greater understanding of the molecular basis of vector-human and host-parasite interactions and provide strategies to build upon these insights to develop interventions to mitigate human morbidity and mortality from malaria.
Indexed as
Identifiers
11832959What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.