Evidence map›Paper›PMID 11831555›Full record

ReviewMolecular neurobiology

Pharmacological modulation of intracellular Ca(2+) channels at the single-channel level.

P Koulen, E C Thrower

Abstract readReview
PubMed Publisher
In one paragraph

Review in Molecular neurobiology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Control of astrocytic CaBiological research · 2024
    Article
  2. Ion channels in dry eye disease.Indian journal of ophthalmology · 2023
    Review
  3. Review
  4. Article
  5. CaCellular and molecular neurobiology · 2019
    Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Polycystin-2 expression and function in adult mouse lacrimal acinar cells.Investigative ophthalmology & visual science · 2011
    Article
  14. Article
  15. Article
  16. Ryanodine receptor channelopathies.Pflugers Archiv : European journal of physiology · 2010
    Review
  17. Article
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

P KoulenDepartment of Pharmacology and Neuroscience, University of North Texas, Fort Worth 76107-2699, USA. pkoulen@hsc.unt.edu
E C Thrower

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Synaptic signaling, memory formation, neuronal development, and neuronal pathology are strongly influenced by the properties of intracellular Ca2+ channels, ryanodine, and inositol 1, 4, 5 trisphosphate receptors. This review will focus on recently developed and discovered pharmacological tools to modulate these channel proteins at the single-channel level. It will allow the readers of Molecular Neurobiology to evaluate the current knowledge on the pharmacological modulation of intracellular Ca2+ channels and to direct future research efforts effectively using available experimental tools and concepts.

Indexed as

AnimalsCalcium ChannelsEthanolInositol 1,4,5-Trisphosphate ReceptorsIntracellular FluidNeuronsPolyaminesReceptors, Cytoplasmic and NuclearRuthenium RedRyanodine Receptor Calcium Release ChannelSignal TransductionSulfhydryl ReagentsSynapsesCalcium ChannelsEthanolInositol 1,4,5-Trisphosphate ReceptorsPolyaminesReceptors, Cytoplasmic and NuclearRuthenium RedRyanodine Receptor Calcium Release ChannelSulfhydryl Reagents

Identifiers

PMID11831555

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.