ReviewSpringer seminars in immunopathology2001
Naive and memory B cells in T-cell-dependent and T-independent responses.
Review in Springer seminars in immunopathology, 2001. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed, 1 synthesis or guideline pooled it.
- T-Cell Dependent Immunogenicity of Protein Therapeutics Pre-clinical Assessment and Mitigation-Updated Consensus and Review 2020.Frontiers in immunology · 2020Pooled it
- The immune microenvironment of HPV-associated cancers: from viral oncogenesis to immunotherapy response.Frontiers in immunology · 2026Review
- Highly variable aggregation and glycosylation profiles and their roles in immunogenicity to protein-based therapeutics.Journal of pharmaceutical sciences · 2025Review
- Development of a semi-automated MHC-associated peptide proteomics (MAPPs) method using streptavidin bead-based immunoaffinity capture and nano LC-MS/MS to support immunogenicity risk assessment in drug development.Frontiers in immunology · 2023Article
- Article
- In Vitro Models for Studying Respiratory Host-Pathogen Interactions.Advanced biology · 2021Review
- Immunological Network in Head and Neck Squamous Cell Carcinoma-A Prognostic Tool Beyond HPV Status.Frontiers in oncology · 2020Review
- TCPro: an In Silico Risk Assessment Tool for Biotherapeutic Protein Immunogenicity.The AAPS journal · 2019Article
- Review
- Use of Reverse Vaccinology in the Design and Construction of Nanoglycoconjugate Vaccines against Burkholderia pseudomallei.Clinical and vaccine immunology : CVI · 2017Article
- Aiolos Overexpression in Systemic Lupus Erythematosus B Cell Subtypes and BAFF-Induced Memory B Cell Differentiation Are Reduced by CC-220 Modulation of Cereblon Activity.Journal of immunology (Baltimore, Md. : 1950) · 2017Article
- Malaria Parasites: The Great Escape.Frontiers in immunology · 2016Review
- A review of quantitative modeling of B cell responses to antigenic challenge.Journal of pharmacokinetics and pharmacodynamics · 2014Review
- Removing T-cell epitopes with computational protein design.Proceedings of the National Academy of Sciences of the United States of America · 2014Article
- B1b cells recognize protective antigens after natural infection and vaccination.Frontiers in immunology · 2014Review
- Follicular dendritic cells in health and disease.Frontiers in immunology · 2012Article
- B-cell tolerance in transplantation: is repertoire remodeling the answer?Expert review of clinical immunology · 2009Article
- T cell epitope: friend or foe? Immunogenicity of biologics in context.Advanced drug delivery reviews · 2009Review
- BLyS inhibition eliminates primary B cells but leaves natural and acquired humoral immunity intact.Proceedings of the National Academy of Sciences of the United States of America · 2008Article
- Targeted cell entry of lentiviral vectors.Molecular therapy : the journal of the American Society of Gene Therapy · 2008Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This review focuses on the properties and roles of distinct subsets among the primary and the memory B lymphocytes regarding their contribution to helper-T-cell-dependent and -independent antibody responses. The naive/memory B cell functions are explained in the context of current concepts on the basic mechanisms of humoral immunity. Differences between murine and human B cells are also discussed.
Indexed as
Identifiers
11826617What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.