ArticleThe Plant cell2002
Repair of damaged DNA by Arabidopsis cell extract.
Article in The Plant cell, 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
27 citing papers in PubMed, 53 citations in OpenAlex.
- Translesion DNA synthesis on pyrimidine dimers by plant organellar DNA polymerases is metal-dependent.Nucleic acids research · 2026Article
- UVH6 regulates osmotic and heat stress tolerance by modulating transcription.Frontiers in plant science · 2025Article
- Base Excision DNA Repair in Plants:International journal of molecular sciences · 2023Review
- Chloroplastic RecA protein fromPhysiology and molecular biology of plants : an international journal of functional plant biology · 2022Article
- Article
- Dyes in aquaculture and reference points for action.EFSA journal. European Food Safety Authority · 2017Article
- Genome stability in the uvh6 mutant of Arabidopsis thaliana.Plant cell reports · 2014Article
- Preparation of efficient excision repair competent cell-free extracts from C. reinhardtii cells.PloS one · 2014Article
- ddm1 plants are sensitive to methyl methane sulfonate and NaCl stresses and are deficient in DNA repair.Plant cell reports · 2012Article
- An epifluorescent attachment improves whole-plant digital photography of Arabidopsis thaliana expressing red-shifted green fluorescent protein.AoB PLANTS · 2012Article
- The conserved factor DE-ETIOLATED 1 cooperates with CUL4-DDB1DDB2 to maintain genome integrity upon UV stress.The EMBO journal · 2011Article
- The Functions of RNA-Dependent RNA Polymerases in Arabidopsis.The arabidopsis book · 2011Article
- Differential sensitivity of Arabidopsis siRNA biogenesis mutants to genotoxic stress.Plant cell reports · 2010Article
- Microsatellite instability in Arabidopsis increases with plant development.Plant physiology · 2010Article
- Single-nucleotide and long-patch base excision repair of DNA damage in plants.The Plant journal : for cell and molecular biology · 2009Article
- Evidence for base excision repair of oxidative DNA damage in chloroplasts of Arabidopsis thaliana.The Journal of biological chemistry · 2009Article
- Plant and fungal Fpg homologs are formamidopyrimidine DNA glycosylases but not 8-oxoguanine DNA glycosylases.DNA repair · 2009Article
- Regulation and role of Arabidopsis CUL4-DDB1A-DDB2 in maintaining genome integrity upon UV stress.PLoS genetics · 2008Article
- CENTRIN2 interacts with the Arabidopsis homolog of the human XPC protein (AtRAD4) and contributes to efficient synthesis-dependent repair of bulky DNA lesions.Plant molecular biology · 2006Article
- Roles of Arabidopsis AtREV1 and AtREV7 in translesion synthesis.Plant physiology · 2005Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
All living organisms have to protect the integrity of their genomes from a wide range of genotoxic stresses to which they are inevitably exposed. However, understanding of DNA repair in plants lags far behind such knowledge in bacteria, yeast, and mammals, partially as a result of the absence of efficient in vitro systems. Here, we report the experimental setup for an Arabidopsis in vitro repair synthesis assay. The repair of plasmid DNA treated with three different DNA-damaging agents, UV light, cisplatin, and methylene blue, after incubation with whole-cell extract was monitored. To validate the reliability of our assay, we analyzed the repair proficiency of plants depleted in AtRAD1 activity. The reduced repair of UV light- and cisplatin-damaged DNA confirmed the deficiency of these plants in nucleotide excision repair. Decreased repair of methylene blue-induced oxidative lesions, which are believed to be processed by the base excision repair machinery in mammalian cells, may indicate a possible involvement of AtRAD1 in the repair of oxidative damage. Differences in sensitivity to DNA polymerase inhibitors (aphidicolin and dideoxy TTP) between plant and human cell extracts were observed with this assay.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.