ArticleThe Plant cell2002
Arabidopsis RGL1 encodes a negative regulator of gibberellin responses.
Article in The Plant cell, 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 147 papers.
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147 citing papers in PubMed, 354 citations in OpenAlex.
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- Strigolactone-induced degradation of SMXL7 and SMXL8 contributes to gibberellin- and auxin-mediated fiber cell elongation in cotton.The Plant cell · 2024Article
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- Analysis Transcriptome and Phytohormone Changes Associated with the Allelopathic Effects of Ginseng Hairy Roots Induced by Different-Polarity Ginsenoside Components.Molecules (Basel, Switzerland) · 2024Article
- The mechanism of low blue light-induced leaf senescence mediated by GmCRY1s in soybean.Nature communications · 2024Article
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- Genome-wide identification and expression analysis of the GRAS gene family under abiotic stresses in wheat (Triticum aestivum L.).Scientific reports · 2023Article
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87 more citing papers are in PubMed but not listed here.
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In Arabidopsis, the DELLA subfamily of GRAS regulatory genes consists of GAI, RGA, RGA-LIKE1 (RGL1), RGL2, and RGL3. GAI and RGA are known to be negative regulators of gibberellin (GA) responses. We found that RGL1 is a similar repressor of GA responses, as revealed by RGL1 gain-of-function and loss-of-function phenotypes. Repression of GA responses in Arabidopsis was conferred by a dominant 35S-rgl1 transgene carrying a DELLA domain deletion analogous to the GA-insensitive gai-1 mutation. As in GA-deficient Arabidopsis, the transgenic plants were dark green dwarfs with underdeveloped trichomes and flowers. Expression levels of GA4, a feedback-regulated GA biosynthetic gene, were increased correspondingly. Conversely, a loss-of-function rgl1 line had reduced GA4 expression and exhibited GA-independent activation of seed germination, leaf expansion, flowering, stem elongation, and floral development, as detected by resistance to the GA biosynthesis inhibitor paclobutrazol. RGL1 plays a greater role in seed germination than do GAI and RGA. The expression profile of RGL1 differed from those of the four other DELLA homologs. RGL1 message levels were predominant in flowers, with transcripts detected in developing ovules and anthers. As with RGA, green fluorescent protein (GFP)-tagged RGL1 protein was localized to the nucleus, but unlike GFP-RGA, there was no degradation after GA treatment. These findings indicate that RGL1 is a partially redundant, but distinct, negative regulator of GA responses and suggest that all DELLA subfamily members might possess separate as well as overlapping roles in GA signaling.
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