ArticleJournal of clinical microbiology2002
Carriage frequency, intensity of carriage, and strains of oral yeast species vary in the progression to oral candidiasis in human immunodeficiency virus-positive individuals.
Article in Journal of clinical microbiology, 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
21 citing papers in PubMed, 111 citations in OpenAlex.
- Polychromatic luminescence and improved antifungal performance of succinic acid in the lattice of L-Lysine monohydrochloride.Saudi journal of biological sciences · 2021Article
- Respiratory Tract Colonization byClinical pulmonary medicine · 2018Article
- Rapid Phenotypic and Genotypic Diversification After Exposure to the Oral Host Niche inGenetics · 2018Article
- Oral Candida spp carriage and periodontal diseases in HIV-infected patients in Ribeirão Preto, Brazil.Revista do Instituto de Medicina Tropical de Sao Paulo · 2017Article
- Prevalence of Candida albicans and non-albicans on the tongue dorsa of elderly people living in a post-disaster area: a cross-sectional survey.BMC oral health · 2017Article
- Prevalence of and risk factors for methicillin-resistantJournal of oral microbiology · 2017Article
- Oral candidiasis among African human immunodeficiency virus-infected individuals: 10 years of systematic review and meta-analysis from sub-Saharan Africa.Journal of oral microbiology · 2017Review
- Yeast oropharyngeal colonization in human immunodeficiency virus-infected patients in central taiwan.Mycopathologia · 2014Article
- Detection of species diversity in oral candida colonization and anti-fungal susceptibility among non-oral habit adult diabetic patients.Journal of natural science, biology, and medicine · 2014Article
- Importance of Diversity in the Oral Microbiota including Candida Species Revealed by High-Throughput Technologies.International journal of dentistry · 2014Review
- Genetic variation of innate immune genes in HIV-infected african patients with or without oropharyngeal candidiasis.Journal of acquired immune deficiency syndromes (1999) · 2010Article
- Oropharyngeal colonization of HIV-infected outpatients in Taiwan by yeast pathogens.Journal of clinical microbiology · 2010Article
- Candida dubliniensis: epidemiology and phenotypic methods for identification.Mycopathologia · 2010Review
- Oral Candida infection and colonization in solid organ transplant recipients.Oral microbiology and immunology · 2009Article
- Candida albicans strain maintenance, replacement, and microvariation demonstrated by multilocus sequence typing.Journal of clinical microbiology · 2006Article
- Oral Candida isolates colonizing or infecting human immunodeficiency virus-infected and healthy persons in Mexico.Journal of clinical microbiology · 2005Article
- Immunopathogenesis of oropharyngeal candidiasis in human immunodeficiency virus infection.Clinical microbiology reviews · 2004Review
- Susceptibility pattern and molecular type of species-specific Candida in oropharyngeal lesions of Indian human immunodeficiency virus-positive patients.Journal of clinical microbiology · 2004Article
- Biofilm-forming ability of Candida albicans is unlikely to contribute to high levels of oral yeast carriage in cases of human immunodeficiency virus infection.Journal of clinical microbiology · 2003Article
- Candida dubliniensis infections in a pediatric population: retrospective identification from clinical laboratory isolates of Candida albicans.Journal of clinical microbiology · 2003Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Candida samples were taken over a period of 2 years from 54 human immunodeficiency virus (HIV)-positive asymptomatic subjects to evaluate changes in yeast carriage, intensity of carriage, and genotype over time. Overall, we found that HIV-positive patients with CD4(+)-cell counts of between 200 and 400/microl had significantly more yeast colonization than healthy control subjects. Of the 54 patients, 11 developed thrush. We found that intensity of carriage in these 11 patients increased significantly in the progression from asymptomatic yeast carrier to an episode of oral thrush. Also, the most common yeast species isolated was Candida albicans; however, we did see a number of patients harboring multiple species at the same time. Using the C. albicans-specific probe Ca3, we found that 54% (n = 6) of the 11 patients who developed thrush maintained genetically similar strains throughout the study period, with minor genetic variations in all patients except one. Forty-six percent of these patients had either multiple strains throughout the study period (n = 2), strain replacement (n = 1), or species replacement (n = 2). Of the patients who had multiple strains, one (I4) was infected by two different strains of Candida dubliniensis distinguished by a recently developed species-specific probe. These results suggest that commensal strains colonizing HIV-positive individuals can undergo alterations prior to producing an episode of thrush.
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