ArticleWorld journal of gastroenterology1998
Two novel gastric cancer-associated genes identified by differential display.
Article in World journal of gastroenterology, 1998. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
3 citing papers in PubMed, 4 citations in OpenAlex.
- A novel gene, GCRG224, is differentially expressed in human gastric mucosa.World journal of gastroenterology · 2003Article
- Expression and function of classical protein kinase C isoenzymes in gastric cancer cell line and its drug-resistant sublines.World journal of gastroenterology · 2002Article
- Differential display of vincristine-resistance-related genes in gastric cancer SGC7901 cell.World journal of gastroenterology · 2002Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimTo clone novel gastric cancer-associated genes and investigate their roles in gastric cancer occurrence.
methodsA method called differential display was used which allows the identification of differentially expressed genes by using PAGE to display PCR-amplified cDNA fragments between gastric cancer cells and normal gastric mucosa cells. These fragments were cloned into plasmid vector pUC18. Homology analysis was made after sequencing these fragments.
resultsTwo novel genes were identified compared with sequences from GenBank. One was registered with the AD number AF 051783.In situ hybridization showed that these two novel genes expressed specifically in gastric cancer tissues.
conclusionThe two novel genes obtained by differential display were confirmed to be gastric cancer-associated genes using in situ hybridization.
Identifiers
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Registered trials
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