Evidence map›Paper›PMID 11809640›Full record

SynthesisBMJ (Clinical research ed.)2002

Use of magnetic resonance angiography to select candidates with recently symptomatic carotid stenosis for surgery: systematic review.

Marie E Westwood, Steven Kelly, Elizabeth Berry, John M Bamford, Michael J Gough, C Mark Airey, James F M Meaney, Linda M Davies, Jane Cullingworth, Michael A Smith

Open access · bronzeAbstract readSystematic Review
In one paragraph

Synthesis in BMJ (Clinical research ed.), 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 71 citations in OpenAlex.

  1. Article
  2. Disappeared pulsatile tinnitus related to petrous segment stenosis of the ICA after relief of the stenosis by stenting.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2013
    Article
  3. Article
  4. Evidence of bias and variation in diagnostic accuracy studies.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2006
    Article
  5. Article
  6. Review
  7. Article
  8. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Marie E WestwoodAcademic Unit of Medical Physics, Centre of Medical Imaging Research, General Infirmary, University of Leeds, Leeds LS1 3EX, UK.
Steven Kelly
Elizabeth Berry
John M Bamford
Michael J Gough
C Mark Airey
James F M Meaney
Linda M Davies
Jane Cullingworth
Michael A Smith
University of Leeds · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo determine if sufficient evidence exists to support the use of magnetic resonance angiography as a means of selecting patients with recently symptomatic high grade carotid stenosis for surgery.

designSystematic review of published research on the diagnostic performance of magnetic resonance angiography, 1990-9.

main outcome measuresPerformance characteristics of diagnostic test.

results126 potentially relevant articles were identified, but many articles failed to examine the performance of magnetic resonance angiography as a diagnostic test at the surgical decision thresholds used in major clinical trials on endarterectomy. 26 articles were included in a meta-analysis that showed a maximal joint sensitivity and specificity of 99% (95% confidence interval 98% to 100%) for identifying 70-99% stenosis and 90% (81% to 99%) for identifying 50-99% stenosis. Only four articles evaluated contrast enhanced magnetic resonance angiography.

conclusionsMagnetic resonance angiography is accurate for selecting patients for carotid endarterectomy at the surgical decision thresholds established in the major endarterectomy trials, but the evidence is not very robust because of the heterogeneity of the studies included. Research is needed to determine the diagnostic performance of the most recent developments in magnetic resonance angiography, including contrast enhanced techniques, as well as to assess the impact of magnetic resonance angiography on surgical decision making and outcomes.

Indexed as

Magnetic Resonance AngiographyPatient SelectionCarotid StenosisEndarterectomy, CarotidHumansROC CurveSensitivity and Specificity

Identifiers

PMID11809640
PMCPMC64789
OpenAlexW2158381538

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.