Evidence map›Paper›PMID 11807686›Full record

ArticleThe Journal of infectious diseases2002

A predominant role for Norwalk-like viruses as agents of epidemic gastroenteritis in Maryland nursing homes for the elderly.

Kim Y Green, Gaël Belliot, Jean Lin Taylor, José Valdesuso, Judy F Lew, Albert Z Kapikian, Feng-Ying C Lin

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of infectious diseases, 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 67 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
67citing papers in PubMed, 3 pooled it
8.6field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

67 citing papers in PubMed, 3 syntheses or guidelines pooled it, 167 citations in OpenAlex.

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  20. Next-generation whole genome sequencing identifies the direction of norovirus transmission in linked patients.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2013
    Article

7 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Kim Y GreenLaboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA. kgreen@niaid.nih.gov
Gaël Belliot
Jean Lin Taylor
José Valdesuso
Judy F Lew
Albert Z Kapikian
Feng-Ying C Lin
National Institutes of Health · USMaryland Department of Health · USNational Institute of Allergy and Infectious Diseases · US

Funding

The Norwalk-like Caliciviruses: Epidemic GastroenteritisZ01AI000897 · NIAID · NIAID EXTRAMURAL ACTIVITIES · PI GREEN, KIM Y. · 2001 to 2008
$3.6M
Live, Attenuated Rotavirus VaccinesZ01AI000341 · NIAID · NIAID EXTRAMURAL ACTIVITIES · PI KAPIKIAN, ALBERT · 1985 to 2008
$1.0M
Intramural NIH HHS Z01 AI000897
6 · The paper itself

Abstract

Stool specimens from 156 Maryland nursing home residents, who became ill during 20 outbreaks of gastroenteritis from November 1987 through February 1988, were analyzed. All tested negative for astroviruses, enteroviruses, Group A rotaviruses, Sapporo-like caliciviruses, and enteric bacteria (i.e., Salmonella, Clostridium, and Shigella species). Eighty-two (52%) were positive for Norwalk-like viruses (NLVs), members of the family Caliciviridae. Six distinct genetic clusters within genogroups I and II of the NLVs were detected; a genogroup II (GII) virus closely related to the Camberwell virus in the NLV GII/4 genetic cluster was the predominant strain. Serologic evidence of infection with > or = 1 NLV was detected in 61 (56%) of 109 patients tested against 3 NLV antigens (i.e., Norwalk, Hawaii, and Toronto viruses). Sixteen (80%) outbreaks met the definition for an NLV outbreak. Taken together with a retrospective analysis of bacterial gastroenteritis in this same setting, these data support a major role for NLVs as etiologic agents of gastroenteritis in elderly persons.

Indexed as

Nursing HomesAgedAmino Acid SequenceAntibodies, ViralCapsidEnzyme-Linked Immunosorbent AssayGastroenteritisHumansMarylandMolecular Sequence DataMultigene FamilyNorovirusOpen Reading FramesSeasonsAntibodies, Viral

Identifiers

PMID11807686
PMCPMC4793396
OpenAlexW2167033546

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.