Evidence map›Paper›PMID 11807081›Full record

ArticleJournal of bacteriology2002

Two "wild-type" variants of Escherichia coli sigma(70): context-dependent effects of the identity of amino acid 149.

Nicole E Baldwin, Andrea McCracken, Alicia J Dombroski

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of bacteriology, 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Nicole E BaldwinDepartment of Microbiology and Molecular Genetics, The University of Texas Health Science Center, Houston, Texas 77030, USA.
Andrea McCracken
Alicia J Dombroski

Funding

SIGMA FACTOR IN DNA BINDING AND TRANSCRIPTION INITIATIONR01GM056453 · NIGMS · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI KAPLAN, SAMUEL · 1998 to 2002
$536k
NIGMS NIH HHS GM56453
6 · The paper itself

Abstract

The identity of amino acid 149 of Escherichia coli sigma(70) has been reported variably as either arginine or aspartic acid. We show that the behavior of both a region 1.2 deletion and a single-amino-acid substitution at position 122 are greatly affected by the identity of amino acid 149.

Indexed as

Genetic VariationAmino AcidsAmino Acid SubstitutionAsparagineAspartic AcidDNA-Directed RNA PolymerasesEscherichia coliSequence DeletionSigma FactorTranscription, GeneticAmino AcidsAsparagineAspartic AcidDNA-Directed RNA PolymerasesRNA polymerase sigma 70Sigma Factor

Identifiers

PMID11807081
PMCPMC134806

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.