ArticleJournal of bacteriology2002
Speed versus efficiency in microbial growth and the role of parallel pathways.
Article in Journal of bacteriology, 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed, 38 citations in OpenAlex.
- Article
- Competing metabolic strategies in a multilevel selection model.Royal Society open science · 2016Article
- Flux balance analysis of ammonia assimilation network in E. coli predicts preferred regulation point.PloS one · 2011Article
- Ecosystem biogeochemistry considered as a distributed metabolic network ordered by maximum entropy production.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2010Article
- Metabolic-network-driven analysis of bacterial ecological strategies.Genome biology · 2009Article
- Robustness in Escherichia coli glutamate and glutamine synthesis studied by a kinetic model.Journal of biological physics · 2008Article
- PdhR (pyruvate dehydrogenase complex regulator) controls the respiratory electron transport system in Escherichia coli.Journal of bacteriology · 2007Article
- A genome-scale metabolic reconstruction for Escherichia coli K-12 MG1655 that accounts for 1260 ORFs and thermodynamic information.Molecular systems biology · 2007Article
- Approaches to biosimulation of cellular processes.Journal of biological physics · 2006Article
- Differences in codon bias cannot explain differences in translational power among microbes.BMC bioinformatics · 2005Article
- An evolutionary scenario for the transition to undifferentiated multicellularity.Proceedings of the National Academy of Sciences of the United States of America · 2003Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
Abstract
Many microorganisms have sets of parallel pathways for ATP production in respiration and for ATP utilization in glutamate synthesis. The alternatives differ in efficiency of ATP production and utilization. The choice among these parallel pathways has been hypothesized to control the speed and efficiency of growth. Thus, the organism should be able to alleviate (or exaggerate) deficiency in one pathway by deleting another. I show here that in Escherichia coli the effect of lack of the glutamate-synthesizing enzyme glutamate dehydrogenase on glucose-limited growth is altered predictably by ndh, cyo, and cyd mutations affecting parallel pathways leading to ATP synthesis in respiration.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.