ArticleJournal of bacteriology2002
Genetic evidence that the uvsE gene product of Deinococcus radiodurans R1 is a UV damage endonuclease.
Article in Journal of bacteriology, 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed, 78 citations in OpenAlex.
- The DR2416/DR2415 two-component system is responsible for the radioresistance of Deinococcus radiodurans.Antonie van Leeuwenhoek · 2025Article
- Radiation-TolerantGenes · 2024Article
- Involvement of Nucleotide Excision Repair and Rec-Dependent Pathway Genes for UV Radiation Resistance inGenes · 2023Article
- DNA repair enzymes of the Antarctic Dry Valley metagenome.Frontiers in microbiology · 2023Article
- In vitro reconstitution of an efficient nucleotide excision repair system using mesophilic enzymes from Deinococcus radiodurans.Communications biology · 2022Article
- Molecular characterization of stress tolerance genes associated with D. indicus strain under extreme environment conditions.Environmental geochemistry and health · 2021Article
- Conservation and diversity of radiation and oxidative stress resistance mechanisms in Deinococcus species.FEMS microbiology reviews · 2019Review
- Cyclic AMP Receptor Protein Acts as a Transcription Regulator in Response to Stresses in Deinococcus radiodurans.PloS one · 2016Article
- Genome-wide transcriptome and antioxidant analyses on gamma-irradiated phases of deinococcus radiodurans R1.PloS one · 2014Article
- DdrA, DdrD, and PprA: components of UV and mitomycin C resistance in Deinococcus radiodurans R1.PloS one · 2013Article
- The Uve1 endonuclease is regulated by the white collar complex to protect cryptococcus neoformans from UV damage.PLoS genetics · 2013Article
- Oxidative stress resistance in Deinococcus radiodurans.Microbiology and molecular biology reviews : MMBR · 2011Review
- Sulfolobus mutants, generated via PCR products, which lack putative enzymes of UV photoproduct repair.Archaea (Vancouver, B.C.) · 2011Article
- A major role of the RecFOR pathway in DNA double-strand-break repair through ESDSA in Deinococcus radiodurans.PLoS genetics · 2010Article
- The evolution of RecD outside of the RecBCD complex.Journal of molecular evolution · 2009Article
- A novel OxyR sensor and regulator of hydrogen peroxide stress with one cysteine residue in Deinococcus radiodurans.PloS one · 2008Article
- Effect of a recD mutation on DNA damage resistance and transformation in Deinococcus radiodurans.Journal of bacteriology · 2007Article
- UV irradiation induces homologous recombination genes in the model archaeon, Halobacterium sp. NRC-1.Saline systems · 2005Article
- Characterization of pathways dependent on the uvsE, uvrA1, or uvrA2 gene product for UV resistance in Deinococcus radiodurans.Journal of bacteriology · 2005Article
- Global transcriptional and proteomic analysis of the Sig1 heat shock regulon of Deinococcus radiodurans.Journal of bacteriology · 2005Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
An in vitro transposition system, developed to facilitate gene disruption in Deinococcus radiodurans R1, has been used to inactivate the gene designated dr1819 in uvrA-1(+) and uvrA-1 backgrounds. dr1819 encodes a protein with homology to a UV DNA damage endonuclease expressed by Schizosaccharomyces pombe. Interruption of dr1819 greatly sensitizes the uvrA-1 strain but not the uvrA-1(+) strain to UV light, indicating that the dr1819 gene product is a component in a DNA repair pathway that can compensate for the loss of nucleotide excision repair in this species. Clones of dr1819 will restore UV resistance to UVS78, a uvrA-1 uvsE strain, indicating that dr1819 and uvsE are the same locus.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.