ReviewRespiratory research2002
Interactions between genes and environmental factors in asthma and atopy: new developments.
Review in Respiratory research, 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
32 citing papers in PubMed, 3 syntheses or guidelines pooled it, 111 citations in OpenAlex.
- Association of the IL-4R Q576R Polymorphism with Pediatric Asthma: a meta-analysis.African health sciences · 2022Pooled it
- Association of FcεRIβ polymorphisms with risk of asthma and allergic rhinitis: evidence based on 29 case-control studies.Bioscience reports · 2018Pooled it
- Association between regulated upon activation, normal T cells expressed and secreted (RANTES) -28C/G polymorphism and asthma risk--a meta-analysis.International journal of medical sciences · 2010Pooled it
- A Narrative Review of Gene-Environment Interactions in Pediatric Pulmonology.Pediatric pulmonology · 2026Review
- Cardiorespiratory and Glycaemic Changes Following Prehospital Nebulised Salbutamol in Acute Asthma: A Mixed Retrospective and Prospective Observational Study.Journal of asthma and allergy · 2026Article
- Impact of antigen loading in tolerogenic nanoparticles to mitigate Th2-mediated allergic lung inflammation.Drug delivery and translational research · 2024Article
- Maternal Exposure to Polychlorinated Biphenyls and Asthma, Allergic Rhinitis and Atopic Dermatitis in the Offspring: The Environmental Health Fund Birth Cohort.Frontiers in pharmacology · 2022Article
- Cytology and molecular study for GSTP1 effect on asthma Iraqi patients.Clinical and molecular allergy : CMA · 2019Article
- Endothelial nitric oxide synthase gene polymorphisms are associated with sensitization to seasonal aeroallergens in asthmatic children.World journal of pediatrics : WJP · 2017Article
- Monoclonal antibodies: the new magic bullets for allergy: IUPHAR Review 17.British journal of pharmacology · 2016Review
- Identification of IL13 C1923T as a Single Nucleotide Polymorphism for Asthma in Children from Mauritius.Pediatric allergy, immunology, and pulmonology · 2015Article
- Atopic dermatitis patients carrying G allele in -1082 G/A IL-10 polymorphism are predisposed to higher serum concentration of IL-10.Archives of medical science : AMS · 2014Article
- Single nucleotide polymorphisms predisposing to asthma in children of Mauritian Indian and Chinese Han ethnicity.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica · 2014Article
- Highly Protective Association of MMP-2-1306C/T Promoter Polymorphism With Asthma in a North Indian Population: A Pilot Study.Allergy, asthma & immunology research · 2014Article
- Genome-wide methylation profiling of the bronchial mucosa of asthmatics: relationship to atopy.BMC medical genetics · 2013Article
- A genome-wide association study of total serum and mite-specific IgEs in asthma patients.PloS one · 2013Article
- RANTES gene polymorphisms and risk of pediatric asthma: A meta-analysis.Experimental and therapeutic medicine · 2012Article
- Association of β(2)-adrenergic receptor polymorphisms with asthma in a North Indian population.Lung · 2012Article
- Article
- Asthma-predictive genetic markers in gene expression profiling of peripheral blood mononuclear cells.Allergy, asthma & immunology research · 2011Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Asthma and associated phenotypes are complex traits most probably caused by an interaction of multiple disease susceptibility genes and environmental factors. Major achievements have occurred in identifying chromosomal regions and polymorphisms in candidate genes linked to or associated with asthma, atopic dermatitis, IgE levels and response to asthma therapy. The aims of this review are to explain the methodology of genetic studies of multifactorial diseases, to summarize chromosomal regions and polymorphisms in candidate genes linked to or associated with asthma and associated traits, to list genetic alterations that may alter response to asthma therapy, and to outline genetic factors that may render individuals more susceptible to asthma and atopy due to environmental changes.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.