ArticleGenetics2002
Genetic variation for phenotypically invariant traits detected in teosinte: implications for the evolution of novel forms.
Article in Genetics, 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
31 citing papers in PubMed, 116 citations in OpenAlex.
- Spliceosome buffers cryptic genetic variation to enforce phenotypic robustness inScience advances · 2026Article
- Genetic architecture of cowpea domestication: QTL mapping and comparison shed new light on the dual domestication events.G3 (Bethesda, Md.) · 2026Article
- Evolution in Response to an Abiotic Stress Shapes Species Coexistence.Ecology letters · 2025Article
- Idiosyncratic and dose-dependent epistasis drives variation in tomato fruit size.Science (New York, N.Y.) · 2023Article
- Identification of a major QTL and genome-wide epistatic interactions for single vs. paired spikelets in a maize-teosinte FMolecular breeding : new strategies in plant improvement · 2022Article
- Combining QTL-seq and linkage mapping to uncover the genetic basis of single vs. paired spikelets in the advanced populations of two-ranked maize×teosinte.BMC plant biology · 2021Article
- Trait variation in extreme thermal environments under constant and fluctuating temperatures.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2019Article
- Assessing elements of an extended evolutionary synthesis for plant domestication and agricultural origin research.Proceedings of the National Academy of Sciences of the United States of America · 2017Article
- Quantitative Genetics Identifies Cryptic Genetic Variation Involved in the Paternal Regulation of Seed Development.PLoS genetics · 2016Article
- Transcriptional Derepression Uncovers Cryptic Higher-Order Genetic Interactions.PLoS genetics · 2015Article
- Cryptic genetic variation: evolution's hidden substrate.Nature reviews. Genetics · 2014Review
- Genetic and environmental factors affecting cryptic variations in gene regulatory networks.BMC evolutionary biology · 2013Article
- Compensatory evolution and the origins of innovations.Genetics · 2013Article
- Degeneracy allows for both apparent homogeneity and diversification in populations.Bio Systems · 2012Article
- Role of pleiotropy in the evolution of a cryptic developmental variation in Caenorhabditis elegans.PLoS biology · 2012Article
- Distinct genetic architectures for male and female inflorescence traits of maize.PLoS genetics · 2011Article
- Article
- Robustness and evolvability.Trends in genetics : TIG · 2010Review
- Identification of a Chr 11 quantitative trait locus that modulates proliferation in the rostral migratory stream of the adult mouse brain.The European journal of neuroscience · 2010Article
- Standing variation and new mutations both contribute to a fast response to selection for flowering time in maize inbreds.BMC evolutionary biology · 2010Article
Corrections and comments
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Authors and funding
2 authors at 2 institutions in 1 country.
Funding
Abstract
How new discrete states of morphological traits evolve is poorly understood. One possibility is that single-gene changes underlie the evolution of new discrete character states and that evolution is dependent on the occurrence of new single-gene mutations. Another possibility is that multiple-gene changes are required to elevate an individual or population above a threshold required to produce the new character state. A prediction of the latter model is that genetic variation for the traits should exist in natural populations in the absence of phenotypic variation. To test this idea, we studied traits that are phenotypically invariant within teosinte and for which teosinte is discretely different from its near relative, maize. By employing a QTL mapping strategy to analyze the progeny of a testcross between an F(1) of two teosintes and a maize inbred line, we identified cryptic genetic variation in teosinte for traits that are invariant in teosinte. We argue that such cryptic genetic variation can contribute to the evolution of novelty when reconfigured to exceed the threshold necessary for phenotypic expression or by acting to modify or stabilize the effects of major mutations.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.