Evidence map›Paper›PMID 11799193›Full record

ArticleJournal of virology2002

Inhibition of duck hepatitis B virus infection by a myristoylated pre-S peptide of the large viral surface protein.

Stephan Urban, Philippe Gripon

Open access · greenAbstract read
In one paragraph

Article in Journal of virology, 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
3.8field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 46 citations in OpenAlex.

  1. Review
  2. Virus entry mediated by hepatitis B virus envelope proteins.World journal of gastroenterology · 2013
    Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Emerging drugs for hepatitis B.Expert opinion on emerging drugs · 2007
    Review
  9. Article
  10. Review
  11. Hepatitis B virus morphogenesis.World journal of gastroenterology · 2007
    Review
  12. Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Study of the early steps of the Hepatitis B Virus life cycle.International journal of medical sciences · 2004
    Article
  20. Infection of a human hepatoma cell line by hepatitis B virus.Proceedings of the National Academy of Sciences of the United States of America · 2002
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 2 countries.

Stephan UrbanZentrum für Molekulare Biologie, Universität Heidelberg (ZMBH), 69120 Heidelberg, Germany. s.urban@med.uni-heidelberg.de
Philippe Gripon
Heidelberg University · DEInstitut de Recherche en Santé, Environnement et Travail · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We have used the duck hepatitis B virus (DHBV) model to study the interference with infection by a myristoylated peptide representing an N-terminal pre-S subdomain of the large viral envelope protein. Although lacking the essential part of the carboxypeptidase D (formerly called gp180) receptor binding site, the peptide binds hepatocytes and subsequently blocks DHBV infection. Since its activity requires an amino acid sequence involved in host discrimination between DHBV and the related heron HBV (T. Ishikawa and D. Ganem, Proc. Natl. Acad. Sci. USA 92:6259-6263, 1995), we suggest that it is related to the postulated host-discriminating cofactor of infection.

Indexed as

Amino Acid SequenceAnimalsDucksHepadnaviridae InfectionsHepatitis B Virus, DuckHepatitis, Viral, AnimalHepatocytesMolecular Sequence DataMyristic AcidPeptidesViral Envelope ProteinsMyristic AcidPeptidesPre-S protein, Duck hepatitis B virusViral Envelope Proteins

Identifiers

PMID11799193
PMCPMC135925
OpenAlexW2112075463

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.