ArticleAntimicrobial agents and chemotherapy2002
Epigallocatechin gallate synergistically enhances the activity of carbapenems against methicillin-resistant Staphylococcus aureus.
Article in Antimicrobial agents and chemotherapy, 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
49 citing papers in PubMed, 144 citations in OpenAlex.
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- Combining Plant Bioactives With Antibiotics for Enhanced Antibiofilm Activity Against UropathogenicAdvances in pharmacological and pharmaceutical sciences · 2025Article
- Enhancing Antibiotic Efficacy with Natural Compounds: Synergistic Activity of Tannic Acid and Nerol with Commercial Antibiotics against Pathogenic Bacteria.Plants (Basel, Switzerland) · 2024Article
- Screening Tests for the Interaction ofAntibiotics (Basel, Switzerland) · 2024Article
- Clinical Evidence on Expansion of Essential Oil-Based Formulation's Pharmacological Activity in Bovine Mastitis Treatment: Antifungal Potential as Added Value.Antibiotics (Basel, Switzerland) · 2024Article
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- In Vitro Antibiofilm Effect of N-Acetyl-L-cysteine/Dry Propolis Extract Combination on Bacterial Pathogens Isolated from Upper Respiratory Tract Infections.Pharmaceuticals (Basel, Switzerland) · 2023Article
- Synergistic Activity of Thymol with Commercial Antibiotics against Critical and High WHO Priority Pathogenic Bacteria.Plants (Basel, Switzerland) · 2023Article
- Epigenetic and Drug Response Modulation of Epigalocaten-In-3-Gallate inAntibiotics (Basel, Switzerland) · 2023Article
- Drug Resistance and Epigenetic Modulatory Potential of Epigallocatechin-3-Gallate Against Staphylococcus aureus.Current microbiology · 2022Article
- Icariin in Combination with Amoxycillin-Clavulanate and Ampicillin, but Not Vancomycin, Increases Antibiotic Sensitivity and Growth Inhibition against Methicillin-ResistantAntibiotics (Basel, Switzerland) · 2022Article
- Effects of Traditional Chinese Medicine and its Active Ingredients on Drug-Resistant Bacteria.Frontiers in pharmacology · 2022Review
- Antibiotic resistance modifying ability of phytoextracts in anthrax biological agent Bacillus anthracis and emerging superbugs: a review of synergistic mechanisms.Annals of clinical microbiology and antimicrobials · 2021Review
- Bacterial Skin Infections in Livestock and Plant-Based Alternatives to Their Antibiotic Treatment.Animals : an open access journal from MDPI · 2021Review
- Inhibition of Biofilm Formation by the Synergistic Action of EGCG-S and Antibiotics.Antibiotics (Basel, Switzerland) · 2021Article
- Antibacterial Activity ofPlants (Basel, Switzerland) · 2020Article
- Targeting Bacterial Biofilms by the Green Tea Polyphenol EGCG.Molecules (Basel, Switzerland) · 2019Review
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Combinations of carbapenems and epigallocatechin gallate (EGCg; a main constituent of tea catechins) showed potent synergy against 24 clinical isolates of methicillin-resistant Staphylococcus aureus (MRSA). MICs of imipenem in the presence of EGCg at 3.125, 6.25, 12.5, and 25 microg/ml, were restored to the susceptible breakpoint (< or =4 microg/ml) for 8, 38, 46, and 75% of the MRSA isolates, respectively. Similar results were also observed for combinations of panipenem or meropenem and EGCg. Therefore, the combinations may be worthy of further evaluation in vivo against MRSA infection.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.