ReviewInternational journal of hematology2001
Function and clinical significance of platelet-derived microparticles.
Review in International journal of hematology, 2001. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
30 citing papers in PubMed, 124 citations in OpenAlex.
- Circulating endothelial-derived activated microparticle: a useful biomarker for predicting one-year mortality in patients with advanced non-small cell lung cancer.BioMed research international · 2014Trial
- Effect of acarbose on platelet-derived microparticles, soluble selectins, and adiponectin in diabetic patients.Journal of thrombosis and thrombolysis · 2009Trial
- Losartan and simvastatin inhibit platelet activation in hypertensive patients.Journal of thrombosis and thrombolysis · 2004Trial
- Increased Platelet Adhesiveness in Patients with Venous Thromboembolic Disease.TH open : companion journal to thrombosis and haemostasis · 2024Article
- Inhibition of PDGFRβ alleviates endothelial cell apoptotic injury caused by DRP-1 overexpression and mitochondria fusion failure after mitophagy.Cell death & disease · 2023Article
- Platelets at the Vessel Wall in Non-Thrombotic Disease.Circulation research · 2023Review
- Efficacy of a Semi Automated Commercial Closed System for Autologous Leukocyte- and Platelet-Rich Plasma (l-prp) Production in Dogs: A Preliminary Study.Animals : an open access journal from MDPI · 2020Article
- A Champion of Host Defense: A Generic Large-Scale Cause for Platelet Dysfunction and Depletion in Infection.Seminars in thrombosis and hemostasis · 2020Review
- Circulating Microparticles in Patients with Symptomatic Carotid Disease Are Related to Embolic Plaque Activity and Recent Cerebral Ischaemia.Cerebrovascular diseases extra · 2019Article
- Platelet-, leucocyte- and red cell-derived microparticles in stored whole blood, with and without leucofiltration, with and without ionising radiation.Blood transfusion = Trasfusione del sangue · 2018Article
- The Role of Platelet Microparticle Associated microRNAs in Cellular Crosstalk.Frontiers in cardiovascular medicine · 2018Article
- Circulating microparticles are prognostic biomarkers in advanced non-small cell lung cancer patients.Oncotarget · 2017Article
- The impact of hyperglycemia and hyperlipidemia on plasma P-selectin and platelet markers after ischemic stroke.Archives of medical science : AMS · 2017Article
- The Usefulness of Platelet-derived Microparticle as Biomarker of Antiplatelet Therapy in Kawasaki Disease.Journal of Korean medical science · 2017Article
- Effects of Chronic Exercise on Endothelial Progenitor Cells and Microparticles in Professional Runners.Arquivos brasileiros de cardiologia · 2017Article
- Human lung cancer-derived microparticles enhanced angiogenesis and growth of hepatoma cells in rodent lung parenchyma.American journal of translational research · 2016Article
- Circulating microparticles enhanced rat vascular wall remodeling following endothelial denudation.American journal of translational research · 2016Article
- The Role of Circulating Platelets Microparticles and Platelet Parameters in Acute Ischemic Stroke Patients.Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association · 2015Article
- Administered circulating microparticles derived from lung cancer patients markedly improved angiogenesis, blood flow and ischemic recovery in rat critical limb ischemia.Journal of translational medicine · 2015Article
- Circulating membrane-derived microvesicles in redox biology.Free radical biology & medicine · 2014Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Microparticles released from platelets (PMPs) may play a role in the normal hemostatic response to vascular injury because they demonstrate prothrombinase activity. PMPs were first observed as released vesicles from platelets following adhesion to vessel walls, and flow cytometry is now the most widely used method for studying PMPs. PMPs are thought to play a role in clinical disease because they express phospholipids that function as procoagulants. High shear stress can initiate both platelet aggregation and shedding of procoagulant-containing PMP, suggesting that PMP generation by high shear stress occurs in small diseased arteries and arterioles under various clinical conditions. In addition, the possibility that PMPs evoke cellular responses in their immediate microenvironments has recently been suggested. Despite many interesting findings, the significance of PMPs in various clinical conditions remains controversial. For example, it is not known whether PMPs found in peripheral blood vessels cause thrombosis, or if they are the results of thrombosis. There has been some question about whether the PMPs found in thromboses are consumed locally, meaning that PMPs circulating in the peripheral blood are not functionally important. Currently, the number of clinical disorders associated with elevated PMPs is increasing.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.