Evidence map›Paper›PMID 11794410›Full record

ArticleJournal of autism and developmental disorders2001

Birth order effects on nonverbal IQ scores in autism multiplex families.

D Spiker, L J Lotspeich, S Dimiceli, P Szatmari, R M Myers, N Risch

Abstract read
PubMed Publisher
In one paragraph

Article in Journal of autism and developmental disorders, 2001. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Immune dysregulation in autism spectrum disorder.European journal of pediatrics · 2014
    Review
  6. Article
  7. Brief report: Asperger's syndrome and sibling birth order.Journal of autism and developmental disorders · 2013
    Article
  8. Article
  9. Article
  10. Article
  11. Brief Report: Relationship between non-verbal IQ and gender in autism.Journal of autism and developmental disorders · 2009
    Article
  12. Brief report: effect of maternal age on severity of autism.Journal of autism and developmental disorders · 2007
    Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

D SpikerDepartment of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, CA 94305-5719, USA.
L J Lotspeich
S Dimiceli
P Szatmari
R M Myers
N Risch

Funding

MAGNETIC RESONANCE IMAGING IN AUTISM DISCORDANT SIBLINGSK01MH001832 · NIMH · STANFORD UNIVERSITY · PI LOTSPEICH, LINDA J · 2000 to 2004
$862k
MOLECULAR GENETICS OF INFANTILE AUTISMR01MH052708 · NIMH · STANFORD UNIVERSITY · PI RISCH, NEIL J · 1995 to 2000
$283k
NEUROTRANSMITTER RECEPTORSP01MH039437 · NIMH · STANFORD UNIVERSITY · PI CIARANELLO, ROLAND D · 1985 to 1993
–
STATISTICAL METHODS AND APPLICATIONS IN HUMAN GENETICSR01HG000348 · NHGRI · YALE UNIVERSITY · PI RISCH, NEIL J · 1990 to 1995
–
NHGRI NIH HHS HG00348NIMH NIH HHS 1 K01 MH01832-01NIMH NIH HHS MH00219NIMH NIH HHS MH39437NIMH NIH HHS MH52708
6 · The paper itself

Abstract

Lord (1992) published a brief report showing a trend for decreasing nonverbal IQ scores with increasing birth order in a sample of 16 autism multiplex families, and urged replication in a larger sample. In this report, analyses of nonverbal IQ scores for a sample of 144 autism multiplex families indicated that nonverbal IQ scores were significantly lower in secondborn compared with firstborn siblings with autism. This birth order effect was independent of gender as well as the age differences within sib pairs. No such birth order effects were found for social or communicative deficits as measured by the Autism Diagnostic Interview-Revised (ADI-R), but there was a modest tendency for increased scores for ritualistic behaviors for the firstborn sibs. Further, there were no gender differences on nonverbal IQ scores in this sample. Results are discussed in terms of implications for genetic studies of autism.

Indexed as

IntelligenceNonverbal CommunicationAutistic DisorderBirth OrderChildFamilyFemaleHumansMalePsychiatric Status Rating ScalesSex FactorsSocial Behavior

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.