ArticleThe Journal of physiology2002
Enhancement of presynaptic calcium current by cysteine string protein.
Article in The Journal of physiology, 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
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Who cites it
15 citing papers in PubMed, 52 citations in OpenAlex.
- Neurons Export Extracellular Vesicles Enriched in Cysteine String Protein and Misfolded Protein Cargo.Scientific reports · 2017Article
- Article
- CSPα-chaperoning presynaptic proteins.Frontiers in cellular neuroscience · 2014Review
- Cysteine string protein limits expression of the large conductance, calcium-activated K⁺ (BK) channel.PloS one · 2014Article
- Cryoloading: introducing large molecules into live synaptosomes.Frontiers in cellular neuroscience · 2014Article
- Quercetin targets cysteine string protein (CSPalpha) and impairs synaptic transmission.PloS one · 2010Article
- Functional role of J domain of cysteine string protein in Ca2+-dependent secretion from acinar cells.American journal of physiology. Gastrointestinal and liver physiology · 2009Article
- Hsp40 couples with the CSPalpha chaperone complex upon induction of the heat shock response.PloS one · 2009Article
- Effective release rates at single rat Schaffer collateral-CA1 synapses during sustained theta-burst activity revealed by optical imaging.The Journal of physiology · 2007Article
- Interaction between constitutively expressed heat shock protein, Hsc 70, and cysteine string protein is important for cortical granule exocytosis in Xenopus oocytes.The Journal of biological chemistry · 2005Article
- The multiple functions of cysteine-string protein analyzed at Drosophila nerve terminals.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2005Article
- A syntaxin 1, Galpha(o), and N-type calcium channel complex at a presynaptic nerve terminal: analysis by quantitative immunocolocalization.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2004Article
- Synaptic vesicles: test for a role in presynaptic calcium regulation.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2004Article
- Syntaxin 1A co-associates with native rat brain and cloned large conductance, calcium-activated potassium channels in situ.The Journal of physiology · 2003Article
- Presynaptic frequency- and pattern-dependent filtering.Journal of computational neuroscienceReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The isolated chick ciliary neuron calyx synapse preparation was used to test cysteine string protein (CSP) action on presynaptic N-type Ca(2+) channels. Endogenous CSP was localized primarily to secretory vesicle clusters in the presynaptic nerve terminal. Introduction of recombinant CSP into the voltage clamped terminal resulted in a prominent increase in Ca(2+) current amplitude. However, this increase could not be attributed to a change in Ca(2+) channel kinetics, voltage dependence, prepulse inactivation, or G protein inhibition but was attributed to the recruitment of dormant channels. Secretory vesicle associated endogenous CSP may play an important role in enhancing Ca(2+) channel activity at the transmitter release site.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.