ArticlePlant physiology2002
Distinct but conserved functions for two chloroplastic NADP-malic enzyme isoforms in C3 and C4 Flaveria species.
Article in Plant physiology, 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed, 55 citations in OpenAlex.
- A milestone in C4 carbon concentration mechanism evolution: structural remodeling of NADP-malic enzyme in Poaceae.Molecular biology and evolution · 2026Article
- Overexpression of chloroplastic Zea mays NADP-malic enzyme (ZmNADP-ME) confers tolerance to salt stress in Arabidopsis thaliana.Photosynthesis research · 2023Article
- ChloroplasticPlants (Basel, Switzerland) · 2021Article
- Dynamic changes of genome sizes and gradual gain of cell-specific distribution of CThe plant genome · 2021Article
- Evidence That Isoprene Emission Is Not Limited by Cytosolic Metabolites. Exogenous Malate Does Not Invert the Reverse Sensitivity of Isoprene Emission to High [COPlant physiology · 2018Article
- Chimeric Structure of Plant Malic Enzyme Family: Different Evolutionary Scenarios for NAD- and NADP-Dependent Isoforms.Frontiers in plant science · 2018Article
- Systems analysis of cis-regulatory motifs in C4 photosynthesis genes using maize and rice leaf transcriptomic data during a process of de-etiolation.Journal of experimental botany · 2016Article
- The Roles of Organic Acids in C4 Photosynthesis.Frontiers in plant science · 2016Review
- Metabolic Reconstruction of Setaria italica: A Systems Biology Approach for Integrating Tissue-Specific Omics and Pathway Analysis of Bioenergy Grasses.Frontiers in plant science · 2016Article
- Getting the most out of natural variation in C4 photosynthesis.Photosynthesis research · 2014Review
- Evolution of the C4 photosynthetic pathway: events at the cellular and molecular levels.Photosynthesis research · 2013Review
- Characterization of the NADP-malic enzymes in the woody plant Populus trichocarpa.Molecular biology reports · 2013Article
- Antisense reduction of NADP-malic enzyme in Flaveria bidentis reduces flow of CO2 through the C4 cycle.Plant physiology · 2012Article
- Evolutionary insights on C4 photosynthetic subtypes in grasses from genomics and phylogenetics.Genome biology and evolution · 2009Article
- Loss of the transit peptide and an increase in gene expression of an ancestral chloroplastic carbonic anhydrase were instrumental in the evolution of the cytosolic C4 carbonic anhydrase in Flaveria.Plant physiology · 2009Article
- Maize cytosolic NADP-malic enzyme (ZmCytNADP-ME): a phylogenetically distant isoform specifically expressed in embryo and emerging roots.Plant molecular biology · 2008Article
- Characterization of the NADP malic enzyme gene family in the facultative, single-cell C4 monocot Hydrilla verticillata.Photosynthesis research · 2007Article
- Expression of an NADP-malic enzyme gene in rice (Oryza sativa. L) is induced by environmental stresses; over-expression of the gene in Arabidopsis confers salt and osmotic stress tolerance.Plant molecular biology · 2007Article
- A comprehensive analysis of the NADP-malic enzyme gene family of Arabidopsis.Plant physiology · 2005Article
- Maize recombinant non-C4 NADP-malic enzyme: a novel dimeric malic enzyme with high specific activity.Plant molecular biology · 2004Article
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In the most common C4 pathway for carbon fixation, an NADP-malic enzyme (NADP-ME) decarboxylates malate in the chloroplasts of bundle sheath cells. Isoforms of plastidic NADP-ME are encoded by two genes in all species of Flaveria, including C3, C3-C4 intermediate, and C4 types. However, only one of these genes, ChlMe1, encodes the enzyme that functions in the C4 pathway. We compared the expression patterns of the ChlMe1 and ChlMe2 genes in developing leaves of Flaveria pringlei (C3) and Flaveria trinervia (C4) and in transgenic Flaveria bidentis (C4). ChlMe1 expression in C4 species increases in leaves with high C4 pathway activity. In the C3 species F. pringlei, ChlMe1 expression is transient and limited to early leaf development. In contrast, ChlMe2 is expressed in C3 and C4 species concurrent with stages in chloroplast biogenesis. Because previous studies suggest that NADP-ME activities generally reflect the level of its mRNA abundance, we discuss possible roles of ChlMe1 and ChlMe2 based on these expression patterns.
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11788758PMC148954W2150512924What OpenQuestion holds
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