ArticleGenes & development2002
A. thaliana TRANSPARENT TESTA 1 is involved in seed coat development and defines the WIP subfamily of plant zinc finger proteins.
Article in Genes & development, 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 84 papers.
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Who cites it
84 citing papers in PubMed, 211 citations in OpenAlex.
- Review
- The Structure, Classification, Functional Diversity and Regulatory Mechanism of Plant C2H2 Transcription Factors.Biology · 2026Review
- MsWIP3 functions as a transcriptional regulator affecting alfalfa (Medicago sativa) response under saline -alkali stress.Plant cell reports · 2026Article
- Article
- Genome-wide identification of the WIP family in foxtail millet (Setaria italica) and functional analysis of SiWIP3 in inhibiting growth in transgenic Arabidopsis thaliana.BMC genomics · 2025Article
- Comprehensive analysis of the INDETERMINATE DOMAIN (IDD) gene family in Marchantia polymorpha brings new insight into evolutionary developmental biology.BMC genomics · 2025Article
- The APETALA2-MYBL2 module represses proanthocyanidin biosynthesis by affecting formation of the MBW complex in seeds of Arabidopsis thaliana.Plant communications · 2024Article
- Integrative analysis of metabolome and transcriptome reveals a dynamic regulatory network of potato tuber pigmentation.iScience · 2023Article
- Genome-wide identification of the C2H2 zinc finger gene family and expression analysis under salt stress in sweetpotato.Frontiers in plant science · 2023Article
- Fine mapping and cloning of a novel BrSCC1 gene for seed coat color in Brassica rapa L.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2023Article
- Transcriptional regulation of proanthocyanidin biosynthesis pathway genes and transcription factors in Indigofera stachyodes Lindl. roots.BMC plant biology · 2022Article
- Expression and Functional Analyses of thePlants (Basel, Switzerland) · 2022Article
- ARF2 positively regulates flavonols and proanthocyanidins biosynthesis in Arabidopsis thaliana.Planta · 2022Article
- Transcriptome analysis reveals cell cycle-related transcripts as key determinants of varietal differences in seed size of Brassica juncea.Scientific reports · 2022Article
- Spatially expressed WIP genes control Arabidopsis embryonic root development.Nature plants · 2022Article
- Genome-Wide Analysis of C2H2 Zinc Finger Gene Family and Its Response to Cold and Drought Stress in Sorghum [International journal of molecular sciences · 2022Article
- Monitoring Apricot (International journal of molecular sciences · 2022Article
- Genome-Wide Identification and Expression Patterns of the C2H2-Zinc Finger Gene Family Related to Stress Responses and Catechins Accumulation inInternational journal of molecular sciences · 2021Article
- Transcriptome Changes Reveal the Molecular Mechanisms of Humic Acid-Induced Salt Stress Tolerance in Arabidopsis.Molecules (Basel, Switzerland) · 2021Article
- Comparative transcriptome analysis of male and female flowers in Spinacia oleracea L.BMC genomics · 2020Article
24 more citing papers are in PubMed but not listed here.
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Seeds of the Arabidopsis thaliana transparent testa 1 mutant (tt1) appear yellow, due to the lack of condensed tannin pigments in the seed coat. The TT1 gene was isolated by reverse genetics using an En-1 transposon mutagenized A. thaliana population. TT1 gene expression was detected in developing ovules and young seeds only, and the gene was shown to encode a nuclear protein. Mutant seeds displayed altered morphology of the seed endothelium in which brown tannin pigments accumulate in wild-type plants, indicating that TT1 is involved in the differentiation of this cell layer. When overexpressed in transgenic A. thaliana plants, TT1 caused aberrant development and organ morphology. The protein contains a novel combination of two TFIIIA-type zinc finger motifs. Closely related motifs were detected in a number of putative proteins deduced from plant genomic and EST sequences. The new protein domain containing this type of zinc finger motifs was designated WIP, according to three strictly conserved amino acid residues. Our data indicate the existence of a small gene family in A. thaliana which is defined by the occurrence of the WIP domain. WIP genes may play important roles in regulating developmental processes, including the control of endothelium differentiation.
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