ArticleVirus genes2001
Characterization of a cluster of late genes of guinea pig cytomegalovirus.
Article in Virus genes, 2001. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
6 citing papers in PubMed, 17 citations in OpenAlex.
- Feeling manipulated: cytomegalovirus immune manipulation.Virology journal · 2009Article
- Analysis of the nucleotide sequence of the guinea pig cytomegalovirus (GPCMV) genome.Virology journal · 2008Article
- Desensitization of herpesvirus-encoded G protein-coupled receptors.Life sciences · 2008Review
- Murine cytomegalovirus with a transposon insertional mutation at open reading frame M35 is defective in growth in vivo.Journal of virology · 2003Article
- A novel CC-chemokine homolog encoded by guinea pig cytomegalovirus.Virus genes · 2002Article
- The human cytomegalovirus UL35 gene encodes two proteins with different functions.Journal of virology · 2002Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Human cytomegalovirus (HCMV) is the most common congenital infection, and is associated with a high rate of morbidity and mortality in the newborn infant. Guinea pig cytomegalovirus (GPCMV) is transmitted through the placenta with resulting fetal infection, and provides an excellent model for the study of fetal cytomegalovirus infection. We have characterized a cluster of late GPCMV genes, identifying GPCMV homologs of the HCMV G protein-coupled receptor gene, UL33; the transcriptional repressor gene, UL34 and two genes encoding tegument proteins, UL32 and UL35. We also identified the GPCMV homolog of UL37, an antiapoptotic gene. Surprisingly, no GPCMV homolog to HCMV UL36 was identified in the same genomic region. Furthermore, two of the predicted GPCMV proteins share greater identity with HHV-6 and/or HHV-7 homologs than with other cytomegalovirus homologs. The identification of GPCMV homologs of conserved viral genes, particularly genes involved in pathogenicity such as the G protein-coupled receptors, will facilitate future analysis of the role of these genes in infections.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.