ArticleKorean journal of radiology
Human in-vivo 31P MR spectroscopy of benign and malignant breast tumors.
Article in Korean journal of radiology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 30 citations in OpenAlex.
- Feasibility ofNMR in biomedicine · 2021Article
- Low SARNMR in biomedicine · 2019Article
- Focus on the glycerophosphocholine pathway in choline phospholipid metabolism of cancer.NMR in biomedicine · 2019Review
- Imaging to study solid tumour origin and progression: lessons from research and clinical oncology.Immunology and cell biology · 2017Review
- Breast Tissue Metabolism by Magnetic Resonance Spectroscopy.Metabolites · 2017Review
- Molecular magnetic resonance imaging in cancer.Journal of translational medicine · 2015Review
- Energy status and metabolism in intracranial space occupying lesions: a prospective 31p spectroscopic study.Journal of clinical and diagnostic research : JCDR · 2014Article
- Metabolic spectroscopy of inflammation in a bleomycin-induced lung injury model using hyperpolarized 1-(13) C pyruvate.NMR in biomedicine · 2014Article
- Cancer stem cell theory and the warburg effect, two sides of the same coin?International journal of molecular sciences · 2014Article
- Magnetic resonance in the detection of breast cancers of different histological types.Magnetic resonance insights · 2013Review
- Breast cancer imaging: a perspective for the next decade.Medical physics · 2008Review
- MR spectroscopy of the breast.La Radiologia medica · 2008Review
- Application of 31P MR spectroscopy to the brain tumors.Korean journal of radiologyArticle
- The adjacent vessel sign on breast MRI: new data and a subgroup analysis for 1,084 histologically verified cases.Korean journal of radiologyArticle
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo assess the potential clinical utility of in-vivo 31P magnetic resonance spectroscopy (MRS) in patients with various malignant and benign breast lesions. MATERIALS AND
methodsSeventeen patients with untreated primary malignant breast lesions (group I), eight patients with untreated benign breast lesions (group II) and seven normal breasts (group III) were included in this study. In-vivo 31P MRS was performed using a 1.5 Tesla MR scanner. Because of the characteristics of the coil, the volume of the tumor had to exceed 12 cc (3 x 2 x 2 cm), with a superoinferior diameter at least 3 cm. Mean and standard deviations of each metabolite were calculated and metabolite ratios, such as PME/PCr, PDE/PCr, T-ATP/PCr and PCr/T-ATP were calculated and statistically analyzed.
resultsSignificant differences in PME were noted between groups I and III (p=0.0213), and between groups II and III (p=0.0213). The metabolite ratios which showed significant differences were PME/PCr (between groups II and III) (p=0.0201), PDE/PCr (between groups I and III, and between groups II and III) (p=0.0172), T-ATP/PCr (between groups II and III) (p=0.0287), and PCr/T-ATP (between groups II and III) (p=0.0287). There were no significant parameters between groups I and II.
conclusionIn-vivo 31P MRS is not helpful for establishing a differential diagnosis between benign and malignant breast lesions, at least with relatively large lesions greater than 3 cm in one or more dimensions.
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